Discriminating between JCPyV and BKPyV in Urinary Virome Data Sets [PDF]
Viruses, 2021 Polyomaviruses are abundant in the human body. The polyomaviruses JC virus (JCPyV) and BK virus (BKPyV) are common viruses in the human urinary tract.
Catherine Putonti +2 more
exaly +8 more sources
JCPyV miR-J1-5p in Urine of Natalizumab-Treated Multiple Sclerosis Patients [PDF]
Viruses, 2021 The use of Natalizumab in Multiple Sclerosis (MS) can cause the reactivation of the polyomavirus JC (JCPyV); this may result in the development of progressive multifocal leukoencephalopathy (PML), a rare and usually lethal disease.
Mario Clerici +2 more
exaly +7 more sources
Therapeutic potential of flavonols in the treatment of JCPyV [PDF]
Microbiology SpectrumJC polyomavirus (JCPyV) is a double-stranded DNA virus that causes progressive multifocal leukoencephalopathy (PML), a demyelinating disease with a high rate of morbidity and mortality. There are limited treatment options for patients diagnosed with PML,
Walter Atwood +2 more
exaly +6 more sources
COS-7 and SVGp12 Cellular Models to Study JCPyV Replication and MicroRNA Expression after Infection with Archetypal and Rearranged-NCCR Viral Strains [PDF]
Viruses, 2022 Since the non-coding control region (NCCR) and microRNA (miRNA) could represent two different and independent modalities of regulating JC polyomavirus (JCPyV) replication at the transcriptional and post-transcriptional levels, the interplay between JC ...
Valeria Pietropaolo +2 more
exaly +7 more sources
Induction of Brain Tumors by the Archetype Strain of Human Neurotropic JCPyV in a Transgenic Mouse Model [PDF]
Viruses, 2021 JC Virus (JCPyV), a member of the Polyomaviridiæ family, is a human neurotropic virus with world-wide distribution. JCPyV is the established opportunistic infectious agent of progressive multifocal leukoencephalopathy, a fatal demyelinating disease ...
Kamel Khalili, Luis Del Valle
exaly +7 more sources
Viruses, 2023 The human neurotropic Polyomavirus JCPyV is the widespread opportunistic causative pathogen of the fatal demyelinating disease progressive multifocal leukoencephalopathy; however, it has also been implicated in the oncogenesis of several types of cancers.
Luis Del Valle
exaly +4 more sources
Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract [PDF]
Virology JournalBackground Human polyomaviruses (HPyVs), JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV), have been found in upper tract urothelial carcinoma UTUC; however, the association of the viral oncogenic factors and clinical characteristics of UTUC remains ...
Chun-Nun Chao +9 more
doaj +4 more sources
Current Perspectives on JC Polyomavirus Transmission and Associated Diseases: Implications for Prevention in Risk Populations [PDF]
VirusesJC polyomavirus (JCPyV) is a worldwide-distributed human virus. Primary infection with JCPyV is usually asymptomatic and followed by a lifelong persistent infection.
Joana M Oliveira +2 more
doaj +2 more sources
Performance of Ultrasensitive Polymerase Chain Reaction Testing for JC Polyomavirus in Cerebrospinal Fluid Compared with Pathological Diagnosis of Progressive Multifocal Leukoencephalopathy [PDF]
VirusesProgressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by the JC polyomavirus (JCPyV). Based on the clinical criteria, PML is diagnosed via polymerase chain reaction (PCR) detection of JCPyV DNA in cerebrospinal fluid (CSF) in
Kenta Takahashi +6 more
doaj +2 more sources
A study on the distribution of BK and JC polyomavirus in discarded donor kidneys [PDF]
Frontiers in TransplantationIntroductionBK polyomavirus (BKPyV) and JC polyomavirus (JCPyV) are thought to establish persistent, low-grade infections in the kidney. However, their specific intrarenal reservoirs remain unclear.
Wouter T. Moest +15 more
doaj +2 more sources