Results 41 to 50 of about 1,462 (171)
The differential presence of human polyomaviruses, JCPyV and BKPyV, in prostate cancer and benign prostate hypertrophy tissues [PDF]
BMC Cancer, 2021 Abstract Background Studies have shown that human polyomavirus infection may be associated with various human cancers. We investigated the potential relationship between the prevalence of JCPyVor BKPyV and prostate cancer (PC) in patients from Taiwan.
Chenghuang Shen +7 more
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JCPyV VP1 Mutations in Progressive Multifocal Leukoencephalopathy: Altering Tropism or Mediating Immune Evasion? [PDF]
Viruses, 2020 Polyomaviruses are ubiquitous human pathogens that cause lifelong, asymptomatic infections in healthy individuals. Although these viruses are restrained by an intact immune system, immunocompromised individuals are at risk for developing severe diseases driven by resurgent viral replication.
Matthew D. Lauver, Aron E. Lukacher
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Complexities of JC Polyomavirus Receptor-Dependent and -Independent Mechanisms of Infection
Viruses, 2022 JC polyomavirus (JCPyV) is a small non-enveloped virus that establishes lifelong, persistent infection in most of the adult population. Immune-competent patients are generally asymptomatic, but immune-compromised and immune-suppressed patients are at ...
Jenna Morris-Love, Walter J. Atwood
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The oncogenic roles of JC polyomavirus in cancer
Frontiers in Oncology, 2022 JC polyomavirus (JCPyV) belongs to the human polyomavirus family. Based on alternative splicing, the early region encodes the large and small T antigens, while the late region encodes the capsid structural proteins (VP1, VP2, and VP3) and the agnoprotein.
Hua-chuan Zheng, Hang Xue, Cong-yu Zhang
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mBio, 2016 The JC and BK human polyomaviruses (JCPyV and BKPyV, respectively) establish lifelong persistent infections in the kidney. In immunosuppressed individuals, JCPyV causes progressive multifocal leukoencephalopathy (PML), a fatal neurodegenerative disease ...
Benedetta Assetta +3 more
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European Journal of Medical Research, 2022 Introduction The human JC polyomavirus (JCPyV) has been detected in colorectal cancer (CRC) tissues and is suggested to contribute to CRC tumorigenesis. The rearrangement of the JCPyV regulatory region is supposedly associated with CRC development.
Chuan-Yin Fang +6 more
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Journal of International Medical Research, 2018 Objectives Human JC polyomavirus (JCPyV) infection has an increased risk of developing progressive multifocal leukoencephalopathy (PML). Different JCPyV subtypes differ in the virulence with which they cause PML. Currently, the JCPyV infection status and
Caiqin Hu +5 more
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Microbiology Spectrum, 2023 JC polyomavirus (JCPyV) is an opportunistic virus that remains in a latent state in the kidneys and lymphoid organs of more than half of the human adult population.
Larise Oberholster +12 more
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Traces of JC polyomavirus in papillary thyroid cancer: a comprehensive study in Iran
Virology Journal, 2022 Background JC polyomavirus (JCPyV) is known to induce solid tumors such as astrocytomas, glioblastomas, and neuroblastomas in experimental animals, and recent studies have shown that the virus may be correlated with carcinogenesis.
Amir Ali Karimi +6 more
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Prevalence of JC Polyomavirus in Patients with Neuroinvasive Disease of Unknown Etiology in Croatia
Medicina, 2023 Background and Objectives: John Cunningham polyomavirus (JCPyV) is a highly prevalent virus in the human population. The prevalence of JCPyV in patients with central nervous system disorders has not been examined extensively. The aim of this study was to
Tatjana Vilibic-Cavlek +6 more
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