Natalizumab-associated progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS): “a case report from Ireland with review of literature, clinical pitfalls and future direction” [PDF]
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021 Background Progressive multifocal leukoencephalopathy (PML) is one of the most serious treatment-related complications that is encountered in patients with multiple sclerosis (MS).
Salman Mansoor +6 more
doaj +2 more sources
Severe Progressive Multifocal Leukoencephalopathy (PML) and Spontaneous Immune Reconstitution Inflammatory Syndrome (IRIS) in an Immunocompetent Patient [PDF]
Frontiers in Immunology, 2019 Background: Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection with JC-virus (JCV), a papova-virus, affecting mostly oligodendrocytes and the white matter of the central nervous system.
Lea Krey +6 more
doaj +2 more sources
Prolonged Headache in a 13-Year-Old Girl With Acute Lymphoblastic Leukemia: A Case of Possible Neuroinflammatory Complication Responsive to Intravenous Immunoglobulin. [PDF]
Clin Case RepABSTRACT Neurological complications in pediatric acute lymphoblastic leukemia (ALL) may result from disease, CNS involvement, or treatment. We report a 13‐year‐old girl with persistent headache and blurred vision suggestive of raised intracranial pressure.
Hadizadeh A +4 more
europepmc +2 more sources
Pembrolizumab for the treatment of Progressive Multifocal Leukoencephalopathy (PML) in a patient with AIDS: A case report and literature review [PDF]
IDCases, 2022 Tulika Chatterjee, Moni Roy
exaly +2 more sources
The Effect of Ocrelizumab on Anti-JC Virus Antibody Index. [PDF]
Brain BehavSynopsis: This study of 553 MS patients found that anti‐JC virus (JCV) antibody indices remain stable during the first 2 years of ocrelizumab treatment. While peripheral B‐cells were significantly depleted and serum immunoglobulins (IgG, IgM, IgA) showed modest declines, the JCV antibody index did not change significantly.
Virupakshaiah A +8 more
europepmc +2 more sources
Development of demyelinating lesions in progressive multifocal leukoencephalopathy (PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain [PDF]
Neuropathology, 2019 Daisuke Ono +2 more
exaly +2 more sources
Progressive multifocal leukoencephalopathy in an HIV patient: A case report and literature review
Clinical Case Reports, 2023 Key Clinical Message Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection of the brain caused by reactivation of the JC virus, which can lead to a lytic infection of oligodendrocytes.
Ting Lei +5 more
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2023 Background Progressive multifocal leukoencephalopathy (PML) - immune reconstitution inflammatory syndrome (IRIS) in people living with HIV/AIDS (PLWHA) has been rarely described in low- and middle-income countries.
Monize Nascimento Santana +5 more
doaj +1 more source
AIDS Research and Therapy, 2020 The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat +3 more
doaj +1 more source
A Cerebellar Tremor in a Patient with Human Immunodeficiency Virus-1 Associated with Progressive Multifocal Leukoencephalopathy [PDF]
Journal of Movement Disorders, 2009 Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) caused by JC virus infection in oligodendrocytes, especially in patients with acquired immunodeficiency syndrome (AIDS).
Hee-Jin Kim, Jae-Jung Lee, Phil Hyu Lee
doaj +1 more source