Severe Progressive Multifocal Leukoencephalopathy (PML) and Spontaneous Immune Reconstitution Inflammatory Syndrome (IRIS) in an Immunocompetent Patient [PDF]
Frontiers in Immunology, 2019 Background: Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection with JC-virus (JCV), a papova-virus, affecting mostly oligodendrocytes and the white matter of the central nervous system.
Georg Berding, , Florian Wegner
exaly +4 more sources
Natalizumab-associated progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS): “a case report from Ireland with review of literature, clinical pitfalls and future direction” [PDF]
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021 Background Progressive multifocal leukoencephalopathy (PML) is one of the most serious treatment-related complications that is encountered in patients with multiple sclerosis (MS).
Salman Mansoor +6 more
doaj +2 more sources
Progressive multifocal leukoencephalopathy (PML)
Clinical Neurology, 2011 Progressive multifocal leukoencephalopathy (PML) is caused by reactivation of latently infected JCV when hosts' immune system is impaired by HIV infection, hematologic diseases, collagen diseases, immunemodulatory therapy and so on. PML was rare but HIV infection and Natalizumab have made it much more common while the prognosis is much better than ...
Masayuki Saijo +2 more
exaly +4 more sources
A Case Report of Progressive Multifocal Leukoencephalopathy (PML) in an Immunocompetent Patient. [PDF]
CureusProgressive multifocal leukoencephalopathy (PML) is a rare but fatal demyelinating disorder resulting from reactivation of latent John Cunningham virus (JCV), which induces demyelinating lytic infection of oligodendrocytes. We report a case of PML in an individual without identifiable immunodeficiency who presented with insidious and progressive ...
Nazneen KS +4 more
europepmc +3 more sources
Pembrolizumab for the treatment of Progressive Multifocal Leukoencephalopathy (PML) in a patient with AIDS: A case report and literature review [PDF]
IDCases, 2022 Tulika Chatterjee +2 more
exaly +2 more sources
Clinical Presentation and Disease Course of 37 Consecutive Cases of Progressive Multifocal Leukoencephalopathy (PML) at a German Tertiary-Care Hospital: A Retrospective Observational Study [PDF]
Frontiers in Neurology, 2021 Manuel A Friese +2 more
exaly +2 more sources
Development of demyelinating lesions in progressive multifocal leukoencephalopathy (PML): Comparison of magnetic resonance images and neuropathology of post‐mortem brain [PDF]
Neuropathology, 2019 Yukiko Shishido-Hara, Takanori Yokota
exaly +2 more sources
Progressive multifocal leukoencephalopathy in an HIV patient: A case report and literature review
Clinical Case Reports, 2023 Key Clinical Message Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection of the brain caused by reactivation of the JC virus, which can lead to a lytic infection of oligodendrocytes.
Ting Lei +5 more
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2023 Background Progressive multifocal leukoencephalopathy (PML) - immune reconstitution inflammatory syndrome (IRIS) in people living with HIV/AIDS (PLWHA) has been rarely described in low- and middle-income countries.
Monize Nascimento Santana +5 more
doaj +1 more source
AIDS Research and Therapy, 2020 The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat +3 more
doaj +1 more source