Results 31 to 40 of about 1,462 (171)

Nested PCR detection of JC polyomavirus large T-antigen in prostate cancer tissues: a case–control analysis in a Sudanese population [PDF]

Journal of the Egyptian National Cancer Institute
Background The potential involvement of JC polyomavirus (JCPyV) in prostate cancer (PCa) remains a subject of debate, as existing in vitro studies have produced conflicting results.
Maria Ahmed Mohamed Higair, Babbiker Mohammed Taher Gorish, Sana Eltahir Abdallah   +2 more
doaj   +2 more sources

Beyond Human Papillomavirus (HPV): Detection of EBV and Polyomaviruses in Cervical and Anal Samples. [PDF]

J Med Virol
ABSTRACT Colorectal and cervical cancers represent an important public health problem worldwide, particularly in Brazil. Colorectal cancer is one of the most frequently diagnosed malignancies worldwide and the most common cancer in both men and woman in Brazil.
Guimarães ACS, Rodrigues LLS, Campos LB, Martinelli KG, Oliveira NSC, Kast WM, Gaydos CA, de Jesus CS, Pilotto JH, Morgado MG, Gheit T, de Paula VS.   +11 more
europepmc   +2 more sources

Next-Generation Sequencing Methods for Sensitive Hepatitis B Viral Genome Analysis: A European Study. [PDF]

J Med Virol
ABSTRACT This multicentre study investigated the utility of next‐generation sequencing (NGS) to detect and generate hepatitis B virus (HBV) genomes in samples of low viral load (from 0.2 to 6207 IU/mL). 23 HBV DNA‐positive plasma samples of genotypes A‐E and one HBV‐negative control sample were assayed blindly via 9 established NGS methods from 6 ...
Fu MX, Perdomo MF, Lumley SF, Ringlander J, Kean K, Reid K, Mayne R, Montaguth OET, Forrest L, Buddle S, Botha JC, Stenbäck JB, Dickson Z, Kent C, Chai H, Byott M, Hannolainen L, Secret S, Airey G, Hedman K, Andersson MI, Ansari MA, Nastouli E, Breuer J, Matthews PC, Golubchik T, Irving WL, Simmonds P, Harvala H.   +28 more
europepmc   +2 more sources

Seroprevalence of polyomaviruses BK and JC in Finnish women and their spouses followed-up for three years

Scientific Reports, 2023
BK (BKPyV) and JC (JCPyV) polyomavirus infections are commonly subclinical and known infrequently to cause serious clinical diseases. Longitudinal follow-up studies regarding JCPyV and BKPyV serological outcomes are scanty.
Hanna K. Laine, Tim Waterboer, Kari Syrjänen, Seija Grenman, Karolina Louvanto, Stina Syrjänen   +5 more
doaj   +1 more source

Colorectal Carcinoma Affected Patients Are Significantly Poor Responders Against the Oncogenic JC Polyomavirus

Frontiers in Immunology, 2021
BackgroundMany investigations reported the association between human tumors and JCPyV, a polyomavirus with oncogenic potential. The association has been supported by studies that found JCPyV footprints in CRC and gliomas of different types. Indeed, JCPyV
Elena Torreggiani, Ilaria Bononi, Silvia Pietrobon, Elisa Mazzoni, Giovanni Guerra, Carlo Feo, Fernanda Martini, Mauro Tognon   +7 more
doaj   +1 more source

Archetype JC Polyomavirus (JCPyV) Prevails in a Rare Case of JCPyV Nephropathy and in Stable Renal Transplant Recipients With JCPyV Viruria [PDF]

The Journal of Infectious Diseases, 2017
JC polyomavirus (JCPyV) is reactivated in approximately 20% of renal transplant recipients, and it may rarely cause JCPyV-associated nephropathy (JCPyVAN). Whereas progressive multifocal leukoencephalopathy of the brain is caused by rearranged neurotropic JCPyV, little is known about viral sequence variation in JCPyVAN owing to the rarity of this ...
Auvinen Eeva, Seppala Hanna M., Helantera Ilkka T., Lautenschlager Irmeli T., Paulin Lars G., Auvinen Petri O. V., Laine Pia K. S., Jahnukainen Timo J., Auvinen Eeva, Seppala Hanna M., Helantera Ilkka T., Lautenschlager Irmeli T., Paulin Lars G., Auvinen Petri O. V., Laine Pia K. S., Jahnukainen Timo J.   +15 more
openaire   +2 more sources

Pseudovirus mimics cell entry and trafficking of the human polyomavirus JCPyV [PDF]

Virus Research, 2013
The normally asymptomatic human polyomavirus, JCPyV, is the causative agent of a rare but fatal demyelinating disease known as progressive multifocal leukoencephalopathy (PML). Individuals at risk for developing PML include those with AIDS, with other underlying immunosuppressive diseases, and in patients treated with immunomodulatory regimens.
Gretchen V, Gee, Bethany A, O'Hara, Aaron, Derdowski, Walter J, Atwood   +3 more
openaire   +2 more sources

Polyomavirus JCPyV and Its Role in the Urinary Tract [PDF]

, 2022
Polyomaviruses are the smallest closed-circular supercoiled double-stranded viruses found in the human microbiota. The polyomavirus JC (JCPyV) is most commonly found within the urinary tract, and prior studies estimate that 20-80% of older adults carry ...
Mormando, Rita Lauren
core   +1 more source

Polyomavirus Wakes Up and Chooses Neurovirulence

Viruses, 2023
JC polyomavirus (JCPyV) is a human-specific polyomavirus that establishes a silent lifelong infection in multiple peripheral organs, predominantly those of the urinary tract, of immunocompetent individuals.
Arrienne B. Butic, Samantha A. Spencer, Shareef K. Shaheen, Aron E. Lukacher   +3 more
doaj   +1 more source

Genetic diversity of human polyomavirus JCPyV in Southern California wastewater [PDF]

Journal of Water and Health, 2008
JC Polyomavirus (JCPyV) has the potential to be used as a viral marker for human waste contamination because at least 40% of the human population excretes this virus through its urine. In addition, each of 6 known subtypes of JCPyV is associated with a specific human ethnicity group, which has allowed for tracing of human migration.
Amana, Rafique, Sunny C, Jiang
openaire   +2 more sources