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T cell therapies for human polyomavirus diseases
Cytotherapy, 2017Rapid restoration of virus-specific T immunity via adoptive transfer of ex vivo generated T cells has been proven as a powerful therapy for patients with advanced cancers and refractory viral infections such as cytomegalovirus (CMV) and Epstein-Barr virus (EBV).
Sarah I, Davies, Pawel, Muranski
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The Polyomavirus, JCV, and Its Involvement in Human Disease
2007The human neurotropic polyomavirus, JC virus (JCV), is the etiologic agent of progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous system that occurs mainly in immunosuppressed patients. JCV has also been found to be associated with human tumors of the brain and other organs.
Kamel, Khalili +2 more
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The role of sialic acid in human polyomavirus infections
Glycoconjugate Journal, 2006JC virus (JCV) and BK virus (BKV) are human polyomaviruses that infect approximately 85% of the population worldwide [1,2]. JCV is the underlying cause of the fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML), a condition resulting from JCV induced lytic destruction of myelin producing oligodendrocytes in the brain [3].
Gretchen V, Gee +4 more
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Absence of the trichodysplasia spinulosa-associated polyomavirus in human pilomatricomas
European Journal of Dermatology, 2011ejd.2011.1395 Auteur(s) : Jean Kanitakis1 jean.kanitakis@univ-lyon1.fr, Siamaque Kazem2, Els Van Der Meijden2, Mariet Feltkamp2 1 Department of Dermatology & Dermatopathology Laboratory, Ed. Herriot Hospital Group, 5 Place d’Arsonval, 69437 Lyon, France 2 Department of Medical Microbiology, University Medical Center, Leiden, The Netherlands Although ...
Kanitakis, J. +3 more
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Evolution of Human Polyomavirus JC: Implications for the Population History of Humans
Journal of Molecular Evolution, 2002The polyomavirus JC virus (JCV), the etiological agent of progressive multifocal leukoencephalopathy, is ubiquitous in the human population, infecting children asymptomatically, then persisting in the kidney. The main mode of transmission of JCV is from parents to children through long-term cohabitation.
Chie, Sugimoto +7 more
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Human Polyomavirus JC and Progressive Multifocal Leukoencephalopathy
2013John Cunningham virus (JCV) is a double-stranded DNA polyomavirus isolated in 1971 by Padgett et al. from the brain of a patient with Hodgkin disease. Viral DNA is transcripted on both strands and it encodes for the early genes counterclockwise and for the late genes clockwise.
MISCHITELLI, MONICA +5 more
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Human Polyomavirus JC and BK Persistent Infection
2007Primary contact with the human polyomaviruses (HPV) is followed by lifelong persistence of viral DNA in its host. The most prominent organs affected are the kidney, the Central Nervous System (CNS)and the hematopoietic system. Under impairment of immune competence limited activation of virus infection can be followed by prolonged virus multiplication ...
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Identification of a new polyomavirus in distinct human populations and tissues
Journal of Medical Virology, 2023Carolina Torres +2 more
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