Results 41 to 50 of about 3,541,387 (305)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The moderating role of HR analytics on the effects of high-performance work systems on the productivity of manufacturing SMEs in Harare CBD

Cogent Business & Management
Understanding the effects of high-performance work systems on productivity in small to medium enterprises (SMEs) can be critical to the sustainability of these firms in Zimbabwe.
Regis Misheal Muchowe, Hazel Mubango, Mavis Soko, Erica Dumba, Esther Chivabvu   +4 more
doaj   +1 more source

DEFINING CHARACTERISTICS AND PARTICULARITIES OF HUMAN RESOURCES MANAGEMENT IN THE REPUBLIC OF MOLDOVA [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2017
In this article are presented the aspects and the defining conceptions of the human resources management, their importance but also the necessity of some major changes in this domain from the autochthonous organisations.
BUICLI OLGA
doaj  

Recognition and Prioritization of Inhibitory Factors of E- Service Deployment [PDF]

پژوهش‌های مدیریت عمومی, 2017
Extended Abstract Information and communication technology contributes to increasing the efficiency and effectiveness of the business. One of the most basic applications of information and communication technology is to use it to create a transformation ...
Abdolali Keshtegar, Mohammad Ghasemi, Mohammad Rezaie Zohan   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

An Exposition of Research Methodology in Management and Social Sciences

Journal of Economic Development, Environment and People, 2013
In writing this paper the author has consciously stood apart from his earlier works and attempted to dispassionately review his own position so that some degree of clarity of thought might emerge in the process.
Sorab Sadri
doaj  

Solving Human Resources Management of Construction Labors Using Mobile Community Network [PDF]

, 2010
A construction labor works on a project based on adetermined interval time. If the construction project is donethen the labor has to find another one.
Amalia, A. (Amalia), Roslidar, R. (Roslidar)   +1 more
core  

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Perceptions of the dimensions of the fairness of affirmative action: A pilot study

South African Journal of Business Management, 2006
The purpose of this study was to identify the dimensions of affirmative action (AA) fairness in order to develop a valid and reliable questionnaire to assess employees’ perceptions of the fairness of AA decisions and practices, and to explore the ...
L. P. Vermeulen, M. Coetzee
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source