Results 161 to 170 of about 22,696 (185)

Quantitative Analysis of Human Telomerase Reverse Transcriptase in Pancreatic Cancer

Clinical Cancer Research, 2006
Abstract Although telomerase activity is a promising diagnostic marker, clinical introduction of this marker for cancer diagnosis is still problematic due to the lack of means of evaluating sample quality. Human telomerase reverse transcriptase (hTERT), one of the subunits of telomerase, is also a promising diagnostic marker.
Kenoki, Ohuchida, Kazuhiro, Mizumoto, Daisuke, Yamada, Hiroshi, Yamaguchi, Hiroyuki, Konomi, Eishi, Nagai, Koji, Yamaguchi, Masazumi, Tsuneyoshi, Masao, Tanaka   +8 more
openaire   +2 more sources

Prognostic Significance of Telomerase Activity and Human Telomerase Reverse Transcriptase Expression in Ampullary Carcinoma

Annals of Surgical Oncology, 2012
Telomerase activity and human telomerase reverse transcriptase (TERT) have been reported as markers of tumor aggressiveness and poor prognosis in several digestive cancers. In the present study, we examined telomerase activity and TERT expression in ampullary carcinoma to determine whether these parameters could be used as indicators of aggressiveness ...
Ryutaro, Sakabe, Yoshiaki, Murakami, Kenichiro, Uemura, Takeshi, Sudo, Yasushi, Hashimoto, Naru, Kondo, Akira, Nakashima, Hiroki, Ohge, Taijiro, Sueda, Eiso, Hiyama   +9 more
openaire   +2 more sources

Significance of immunological detection of human telomerase reverse transcriptase: re-evaluation of expression and localization of human telomerase reverse transcriptase.

The American journal of pathology, 2003
Human telomerase reverse transcriptase (hTERT) is a catalytic subunit of telomerase and is a potentially useful diagnostic marker for cancers. There have been few studies in which immunological detection of hTERT has been attempted and its subcellular localization has not been precisely defined.
Satoru, Kyo, Kenkichi, Masutomi, Yoshiko, Maida, Taro, Kanaya, Noriyuki, Yatabe, Mitsuhiro, Nakamura, Masaaki, Tanaka, Mitsuko, Takarada, Isamu, Sugawara, Seishi, Murakami, Takahiro, Taira, Masaki, Inoue   +11 more
openaire   +1 more source

Expression of Human Telomerase Reverse Transcriptase in Laryngeal Tissues

Otolaryngology–Head and Neck Surgery, 2004
ProblemTelomerase is believed to play a major role in transforming cells (immortalization) to carcinoma. Its activity has been detected in 90% of human cancers. We evaluated telomerase activity in laryngeal carcinoma patients who underwent surgery for cure through the immunohistochemical detection of human telomerase reverse transcriptase (hTERT ...
Ramon A Franco, Yongyuth Wasinwong
openaire   +1 more source

Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization

International Journal of Oncology, 2002
Telomerase activity is present in most malignant tumors and provides a mechanism for unlimited replication of neoplastic cells. Expression of the gene encoding human telomerase reverse transcriptase (hTERT), the telomerase catalytic subunit gene, is associated with telomerase activity, and it is overexpressed in most colorectal carcinomas.
Makoto, Kammori, Hajime, Kanauchi, Ken-Ichi, Nakamura, Masaki, Kawahara, Thomas K, Weber, Ken-Ichi, Mafune, Michio, Kaminishi, Kaiyo, Takubo   +7 more
openaire   +2 more sources

Human telomerase reverse transcriptase and telomeres in cancer

Journal of Current Oncology, 2021
Anurag Mehta, Shrinidhi Nathany
openaire   +1 more source

Immunoprecipitation of Human Telomerase Reverse Transcriptase with Telomerase Activity

Analytical Biochemistry, 2001
J M, Kraveka, D, Schady, L M, Obeid, B, Ogretmen   +3 more
openaire   +2 more sources

Detection of telomerase activity, human telomerase RNA, and telomerase reverse transcriptase in human hepatocellular carcinoma

Gastroenterology, 2000
Masaki Shimojima, Fumihiko Komine, Hiroshi Aoki, Toshihiro Shimizu, Tamiko Kaneko, Miki Kaneko, Mitsuhiko Moriyama, Yasuyuki Arakawa   +7 more
openaire   +1 more source

Possible Regulation of Telomerase Activity by Transcription and Alternative Splicing of Telomerase Reverse Transcriptase in Human Melanoma

Journal of Investigative Dermatology, 2001
Raffaella Villa, Marco Folini, Maria Grazia Daidone   +2 more
exaly  

Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma

Cancer, 2006
Hua He, Marie C M Lin, Bing Zou
exaly