Results 161 to 170 of about 40,478 (236)

Human telomerase reverse transcriptase promotes the epithelial to mesenchymal transition in lung cancer cells by enhancing c-MET upregulation. [PDF]

Heliyon, 2022
Prasad RR, Mishra DK, Kumar M, Yadava PK.   +3 more
europepmc   +1 more source

A three-state model for the regulation of telomerase by TERRA and hnRNPA1 [PDF]

, 2017
Telomeres, the physical ends of eukaryotic chromosomes, are transcribed into telomeric repeat-containing RNA (TERRA), a large non-coding RNA, which forms an integral part of telomeric heterochromatin.
Lingner, Joachim, Redon, Sophie, Zemp, Ivo   +2 more
core  

ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell‐Type Dependent and Tied to Ceramide Homeostasis

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
ORMDL proteins in the endoplasmic reticulum (ER) negatively regulate serine palmitoyltransferase (SPT) activity in response to the rate of de novo sphingolipid synthesis. Disruption of ceramide homeostasis by myriocin or fumonisin B1 (FB1) appears to destabilize the ORMDL‐SPT complex, leading to ORMDL degradation as a feedback mechanism.
Michal Mrkacek, Magda Tumova, Alex Puskasu, Pavol Utekal, Marek Vrbacky, Ladislav Kuchar, Petr Draber, Viktor Bugajev   +7 more
wiley   +1 more source

Retraction Statement: Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition. [PDF]

Mol Oncol, 2023
europepmc   +1 more source

SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression. [PDF]

Mol Oncol, 2021
Diao C, Guo P, Yang W, Sun Y, Liao Y, Yan Y, Zhao A, Cai X, Hao J, Hu S, Yu W, Chen M, Wang R, Li W, Zuo Y, Pan J, Hua C, Lu X, Fan W, Zheng Z, Deng W, Luo G, Guo W.   +22 more
europepmc   +1 more source

Usefulness of Cell-Free Human Telomerase Reverse Transcriptase Mutant DNA Quantification in Blood for Predicting Hepatocellular Carcinoma Treatment Efficacy. [PDF]

Hepatol Commun, 2021
Muraoka M, Maekawa S, Katoh R, Komiyama Y, Nakakuki N, Takada H, Matsuda S, Suzuki Y, Sato M, Tatsumi A, Miura M, Amemiya F, Shindo H, Takano S, Fukasawa M, Yamauchi K, Yamaguchi T, Nakayama Y, Inoue T, Enomoto N.   +19 more
europepmc   +1 more source

Synergistic Effects of Resistin and Visfatin as Adipocyte Derived Hormones on Telomerase Gene Expression in AGS Gastric Cancer Cell Line

Acta Medica Iranica, 2017
Recently suggested that adipocytokines may play a role in pathogenesis and progression of certain cancers, especially in gastric cancer. The previous study showed Resistin and Visfatin, as adipocyte derived hormones, separately increases telomerase ...
Masoumeh Mohammadi, Nosratollah Zarghami, Mehdi Hedayati, Sara Ghaemmaghami   +3 more
doaj  

A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT). [PDF]

Front Oncol, 2022
Maggadóttir SM, Kvalheim G, Wernhoff P, Sæbøe-Larssen S, Revheim ME, Josefsen D, Wälchli S, Helland Å, Inderberg EM.   +8 more
europepmc   +1 more source

Triptolide inhibits human telomerase reverse transcriptase by downregulating translation factors SP1 and c-Myc in Epstein-Barr virus-positive B lymphocytes. [PDF]

Oncol Lett, 2021
Long C, Xu QB, Ding L, Yang L, Ji W, Gao F, Ji Y.   +6 more
europepmc   +1 more source

Cell membrane breakage and triggering T cell infiltration are involved in human telomerase reverse transcriptase (hTERT) promoter-driven novel peptide KK-64 for liver cancer gene therapy. [PDF]

Bioengineered, 2021
Lu Y, Ma J, Lin J, Tian Y, Ma Y, Wang W, Li J, Zhang H, Jiao P.   +8 more
europepmc   +1 more source