Results 141 to 150 of about 23,184 (172)

Detection of telomerase activity, telomerase RNA component, and telomerase reverse transcriptase in human hepatocellular carcinoma

Hepatology Research, 2004
The aim of this study was to estimate the correlation between telomerase activity and the expression of human telomerase RNA component (hTERC), human telomerase reverse transcriptase (hTERT) in patients with hepatocellular carcinoma (HCC), and to analyze the influence of the nucleotide homology of the hTERC template region on telomerase activity.
Mitsuhiko Moriyama, Hisashi Hisatomi, Yasuyuki Arakawa   +2 more
exaly   +3 more sources

ESTABLISHMENT OF AN IN VIVO MENINGIOMA MODEL WITH HUMAN TELOMERASE REVERSE TRANSCRIPTASE

Neurosurgery, 2007
The lack of meningioma models has hindered research on the pathogenesis and treatment of this commonly diagnosed primary brain tumor. Animal models of meningioma have been difficult to develop, especially those derived from Grade I tumors, which display very slow growth rates, senesce at early passages, and infrequently survive as explants in vivo.
Theresa G, Cargioli, Hasan C, Ugur, Naren, Ramakrishna, Jennifer, Chan, Peter M, Black, Rona S, Carroll   +5 more
openaire   +2 more sources

Quantitative Analysis of Human Telomerase Reverse Transcriptase in Pancreatic Cancer

Clinical Cancer Research, 2006
Abstract Although telomerase activity is a promising diagnostic marker, clinical introduction of this marker for cancer diagnosis is still problematic due to the lack of means of evaluating sample quality. Human telomerase reverse transcriptase (hTERT), one of the subunits of telomerase, is also a promising diagnostic marker.
Kenoki, Ohuchida, Kazuhiro, Mizumoto, Daisuke, Yamada, Hiroshi, Yamaguchi, Hiroyuki, Konomi, Eishi, Nagai, Koji, Yamaguchi, Masazumi, Tsuneyoshi, Masao, Tanaka   +8 more
openaire   +2 more sources

Prognostic Significance of Telomerase Activity and Human Telomerase Reverse Transcriptase Expression in Ampullary Carcinoma

Annals of Surgical Oncology, 2012
Telomerase activity and human telomerase reverse transcriptase (TERT) have been reported as markers of tumor aggressiveness and poor prognosis in several digestive cancers. In the present study, we examined telomerase activity and TERT expression in ampullary carcinoma to determine whether these parameters could be used as indicators of aggressiveness ...
Ryutaro, Sakabe, Yoshiaki, Murakami, Kenichiro, Uemura, Takeshi, Sudo, Yasushi, Hashimoto, Naru, Kondo, Akira, Nakashima, Hiroki, Ohge, Taijiro, Sueda, Eiso, Hiyama   +9 more
openaire   +2 more sources

Significance of immunological detection of human telomerase reverse transcriptase: re-evaluation of expression and localization of human telomerase reverse transcriptase.

The American journal of pathology, 2003
Human telomerase reverse transcriptase (hTERT) is a catalytic subunit of telomerase and is a potentially useful diagnostic marker for cancers. There have been few studies in which immunological detection of hTERT has been attempted and its subcellular localization has not been precisely defined.
Satoru, Kyo, Kenkichi, Masutomi, Yoshiko, Maida, Taro, Kanaya, Noriyuki, Yatabe, Mitsuhiro, Nakamura, Masaaki, Tanaka, Mitsuko, Takarada, Isamu, Sugawara, Seishi, Murakami, Takahiro, Taira, Masaki, Inoue   +11 more
openaire   +1 more source

Immunoprecipitation of Human Telomerase Reverse Transcriptase with Telomerase Activity

Analytical Biochemistry, 2001
J M, Kraveka, D, Schady, L M, Obeid, B, Ogretmen   +3 more
openaire   +2 more sources

Human telomerase reverse transcriptase and telomeres in cancer

Journal of Current Oncology, 2021
Anurag Mehta, Shrinidhi Nathany
openaire   +1 more source

miR-195-5p regulates cell proliferation, apoptosis, and invasion of thyroid cancer by targeting telomerase reverse transcriptase

Bioengineered, 2021
Fei Le, Fenqian Yuan
exaly  

Detection of telomerase activity, human telomerase RNA, and telomerase reverse transcriptase in human hepatocellular carcinoma

Gastroenterology, 2000
Masaki Shimojima, Fumihiko Komine, Hiroshi Aoki, Toshihiro Shimizu, Tamiko Kaneko, Miki Kaneko, Mitsuhiko Moriyama, Yasuyuki Arakawa   +7 more
openaire   +1 more source

Possible Regulation of Telomerase Activity by Transcription and Alternative Splicing of Telomerase Reverse Transcriptase in Human Melanoma

Journal of Investigative Dermatology, 2001
Marco Folini, Nadia Zaffaroni, Maria Grazia Daidone   +2 more
exaly