Results 131 to 140 of about 24,740 (216)

In Vitro Expansion of Human Hepatocytes is Restricted by Telomere-Dependent Replicative Aging

Cell Transplantation, 2003
Currently, different techniques to expand human hepatocytes in vitro are being investigated to generate enough cells for liver-directed cell therapies.
Henning Wege, Michael S. Chui, Hai T. Le, Stephen C. Strom, Mark A. Zern   +4 more
doaj   +1 more source

Mechanism of Human Telomerase Reverse Transcriptase (hTERT) Regulation and Clinical Impacts in Leukemia. [PDF]

Genes (Basel), 2021
Yik MY, Azlan A, Rajasegaran Y, Rosli A, Yusoff NM, Moses EJ.   +5 more
europepmc   +1 more source

Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene. [PDF]

Proc Natl Acad Sci U S A, 2021
Xu T, Cheng, Zhao Y, Zhang J, Zhu X, Zhang F, Chen G, Wang Y, Yan X, Robertson GP, Gaddameedhi S, Lazarus P, Wang S, Zhu J.   +13 more
europepmc   +1 more source

The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma. [PDF]

Oxid Med Cell Longev, 2021
Ding X, Nie Z, She Z, Bai X, Yang Q, Wang F, Wang F, Geng X.   +7 more
europepmc   +1 more source

Correlation between radiation-induced telomerase activity and human telomerase reverse transcriptase mRNA expression in HeLa cells

, 2006
Purpose: To quantify and correlate human telomerase reverse transcriptase (hTERT) mRNA expression with telomerase activity (TA) after ionizing irradiation of HeLa cells.
Satra, M., Papanikolaou, V., Theodorou, K., Kappas, C., Tsougos, I., Tsezou, A.   +5 more
core   +1 more source

Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations

, 2015
AIM: To determine the mutation status of human telomerase reverse transcriptase gene (TERT) promoter region in hepatocellular carcinoma (HCC) from different geographical ...
Ozturk, Mehmet, YILDIZ, GÖKHAN, Cevik, Dilek   +2 more
core   +1 more source

Knockdown of tankyrase 1 inhibits the progression of gastric adenocarcinoma via regulating human telomerase reverse transcriptase and telomeric repeat binding factor 1. [PDF]

J Gastrointest Oncol, 2022
Liu W, Zhu JJ, Liu YY, Tang NN, Wang Y, Jiang B, Wang LL, Wang YX, Xie MP, Wang XY.   +9 more
europepmc   +1 more source

Human telomerase reverse transcriptase promotes the epithelial to mesenchymal transition in lung cancer cells by enhancing c-MET upregulation. [PDF]

Heliyon, 2022
Prasad RR, Mishra DK, Kumar M, Yadava PK.   +3 more
europepmc   +1 more source

Telomerase reverse transcriptase fragments and uses thereof

, 2003
The invention provides compositions comprising fragments of human telomerase reverse transcriptase (hTERT) which can lead to telomere dysfunction in a cell and reduction of growth and tumorigenicity in cancer cells.

core  

Retraction Statement: Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition. [PDF]

Mol Oncol, 2023
europepmc   +1 more source