The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes +6 more
wiley +1 more source
Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer. [PDF]
Kato T +8 more
europepmc +2 more sources
Research Progress on G-Quadruplexes in Human Telomeres and Human Telomerase Reverse Transcriptase (hTERT) Promoter. [PDF]
Gu W +9 more
europepmc +1 more source
On the basis of its predicted homology to human telomerase reverse transcriptase (hTERT), a cDNA for Arabidopsis thaliana TERT (AtTERT) has now been isolated from cultured cells. The cDNA contains an open reading frame of 3372 bp, encoding a protein with
Hongtu Liu +7 more
core +1 more source
Clinical application of the anti-human telomerase reverse transcriptase (hTERT) antibody (SCD-A7) immunocytochemistry in liquid-based urine cytology: A prospective, single institute study. [PDF]
Moon JH +4 more
europepmc +1 more source
Structural studies of three enzymes: telomerase, the methyltransferase CobJ and pectate lyase
PhDThis thesis investigates the structure and function of three enzymes of biotechnological and biomedical interest: telomerase from Caenorhabtidis elegans, pectate lyase from Bacillus subtilis and the methyltransferase CobJ from Rhodobacter capsulatus.
To, Teng Teng
core
Human Telomerase Reverse Transcriptase as a Therapeutic Target of Dihydroartemisinin for Esophageal Squamous Cancer. [PDF]
Li Q +11 more
europepmc +1 more source
Valproic acid suppresses telomerase activity and downregulates hTERT expression in human colorectal cancer cells [PDF]
Background: Colorectal cancer (CRC) is a leading cause of cancer-related mortality, underscoring the need for novel therapies targeting key drivers of tumor progression.
Mohsen Tatar +3 more
doaj
Implications of risk conferred by 5p15.33 loci genetic variants; human telomerase reverse transcriptase rs2736098 and rs2736100 in predisposition of bladder cancer. [PDF]
Anwar I +10 more
europepmc +1 more source
Control of gene expression in prostate epithelial cell differentiation hierarchy [PDF]
The aim of present investigation is to elucidate the complex stem cell (SC) dynamics within prostate cancer, which can be exploited to design novel diagnostic and therapeutic strategies for the management of prostate cancer.
Rane, Jayant
core

