Results 231 to 240 of about 121,366 (309)

Hypericin-photodynamic therapy induces human umbilical vein endothelial cell apoptosis. [PDF]

Sci Rep, 2015
Zhang Q, Li ZH, Li YY, Shi SJ, Zhou SW, Fu YY, Zhang Q, Yang X, Fu RQ, Lu LC.   +9 more
europepmc   +1 more source

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

The effect of antihypertensive treatment on longitudinal changes in PLGF and sFlt‐1 in women with new onset hypertension in pregnancy

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In pregnant women with new‐onset hypertension starting antihypertensives, some achieve tight BP control within a week (Group 1‐blue line), while others respond slower (Group 2‐red line). Group 1 showed higher Log10PLGF levels, but Log10sFlt‐1 did not differ between groups. Over time, Log10PLGF declined in both groups, while Log10sFlt‐1 remained stable.
Edward Tyrell, Katherine G. Y. Lau, Martyna Bednorz, Kypros H. Nicolaides, Nikos A. Kametas   +4 more
wiley   +1 more source

Identification of Autologous Tissue Sources and Optimization of a Treatment Method for Intraoperative Manufacturing of Heart Valve Constructs

Artificial Organs, EarlyView.
The use of autologous connective tissue, such as pericardium or peritoneum, combined with controlled tissue treatment, has the potential to result in a more durable heart valve prosthesis than current commercial prostheses. ABSTRACT Introduction Valvular heart disease remains a leading cause of morbidity and mortality. Current biological and mechanical
Marvin Steitz, Mahamuda Badhon Khan, Katharina Fritsch, Alexander Breitenstein‐Attach, Jana Katharina Betty Korbacher, Jordi Joaquin Modolell Y Mainou, Katrin Schrimpf, Robert Ramm, Sara Knigge, Katja Eildermann, Georg Arlt, Antonia Schulz, Jonathan Frederik Sebastian Kiekenap, Boris Warnack, Peter Kramer, Frank Edelmann, Felix Berger, Boris Schmitt   +17 more
wiley   +1 more source

Cytoprotective Effect of Antioxidant Pentapeptides from the Protein Hydrolysate of Swim Bladders of Miiuy Croaker (Miichthys miiuy) against H₂O₂-Mediated Human Umbilical Vein Endothelial Cell (HUVEC) Injury. [PDF]

Int J Mol Sci, 2019
Cai SY, Wang YM, Zhao YQ, Chi CF, Wang B.   +4 more
europepmc   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

British Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig, Yusuf C. Erdoğan, Benjamin Gottschalk, Michael Gruber, Andrea Groselj‐Strele, Sandra Burgstaller, Wolfgang F. Graier, Roland Malli   +7 more
wiley   +1 more source

Novel anticancer combination therapies using replication-selective oncolytic adenoviruses and chemotherapeutics [PDF]

, 2011
Hammarén Busch, Kristina
core   +1 more source

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

Cell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu, Sheng‐Jie Chang, Shuo Wang, Xiao‐Wei Liu, Shan‐Jin Wang   +4 more
wiley   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source