Results 1 to 10 of about 77,921 (314)
Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Metformin (Met) and Liraglutide (Lira) have been approved to treat type 2 diabetes mellitus and have cardioprotective effects. Materials and Methods: Human umbilical vein endothelial cells (HUVECs) were incubated with Met, Lira, or their ...
Amir Shadboorestan +7 more
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Frontiers in Bioscience-Landmark, 2022 Background: Long non-coding RNA (lncRNA) hypoxia inducible factor 1α-antisense RNA 1 (HIF1A-AS1) serves critical roles in cardiovascular diseases (CVDs). Vascular endothelial cells (VECs) are vulnerable to stimuli.
Zhiqiang Gong +7 more
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Clinical and Experimental Hypertension, 2023 Background Atherosclerosis has been recognized as a chronic inflammation initiated by dysfunction of endothelial cell that contributes to the increased morbidity and mortality of severe cardiovascular events.
Huai Yu, Hui Cao, Hang Yu
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Animal Cells and Systems, 2022 Although simvastatin has been shown to inhibit vascular permeability, which might be amplified via gap junction intercellular communication (GJIC), the underlying mechanism of action remains unclear.
Xiwen Ling +3 more
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Pharmaceutical Biology, 2021 Context The traditional drying method, sun drying, for Chrysanthemum morifolium Ramat. cv. Hang-ju (Compositae) (HJ) is widely replaced by sulphur fumigation (SF), which has an unknown effect on its efficacy.
Hongyan Ma +9 more
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LncRNA XIST regulates atherosclerosis progression in ox-LDL-induced HUVECs
Open Medicine, 2021 Long noncoding RNAs (lncRNAs) have been verified as vital regulators in human disease, including atherosclerosis. However, the precise role of X-inactive-specific transcript (XIST) in atherosclerosis remains unclear.
Gao Hongmei, Guo Zhaohui
doaj +1 more source
The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization [PDF]
, 2011 Angiogenesis, or neovascularization, is a finely balanced process controlled by pro- and anti-angiogenic factors. Vascular endothelial growth factor (VEGF) is a major pro-angiogenic factor, whereas pigment epithelial-derived factor (PEDF) is the most ...
Crawford, Ross, Fan, Wei, Xiao, Yin
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Investigation of the marine compound spongistatin 1 links the inhibition of PKCα translocation to nonmitotic effects of tubulin antagonism in angiogenesis [PDF]
, 2009 The aims of the study were to meet the demand of new tubulin antagonists with fewer side effects by characterizing the antiangiogenic properties of the experimental compound spongistatin 1, and to elucidate nonmitotic mechanisms by which tubulin ...
Bruns, Christiane J. +7 more
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Gülhane Tıp Dergisi, 2022 Aims:Angiotensin II (Ang II) causes endothelial cell damage. Oxidative stress is involved in the pathophysiology of cardiovascular diseases via transforming growth factor-beta 1 (TGF-β1).
Zehra Çiçek +2 more
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Galectin-1 Regulates RNA Expression and Alternative Splicing of Angiogenic Genes in HUVECs
Frontiers in Bioscience-Landmark, 2023 Background: Angiogenesis is essential for tissue development, and therefore its dysregulation can cause various diseases, including cerebrovascular disease. Galectin-1, encoded by the lectin galactoside-binding soluble-1 gene (LGALS1), has critical roles
Jiajun Wei +3 more
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