Results 11 to 20 of about 77,921 (314)
Autophagy in homocysteine‑induced HUVEC senescence
Experimental and Therapeutic Medicine, 2023 The senescence of vascular endothelial cells (VECs) drives the occurrence and development of cardiovascular disease (CVD). Homocysteine (HCY) is a general risk factor for age-associated CVDs. Autophagy, an evolutionarily conserved lysosomal protein degradation pathway, serves a part in VEC senescence.
Zhang, Yexi +7 more
openaire +2 more sources
Effect of Sphingomyelinase-Treated LDLs on HUVECs
Molecules, 2023 Low-density lipoproteins (LDLs) exert a key role in the transport of esterified cholesterol to tissues. Among the atherogenic modifications of LDLs, the oxidative modification has been mainly investigated as a major risk factor for accelerating atherogenesis.
Angelica Giuliani +8 more
openaire +3 more sources
YULINK regulates vascular formation in zebrafish and HUVECs
Biological Research, 2023 AbstractBackgroundThe distinct arterial and venous cell fates are dictated by a combination of various genetic factors which form diverse types of blood vessels such as arteries, veins, and capillaries. We report here that YULINK protein is involved in vasculogenesis, especially venous formation.MethodsIn this manuscript, we employed gene knockdown ...
Hsin-Hung Lin +4 more
openaire +3 more sources
Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway [PDF]
, 2016 open15Over 10 million people every year become infected by Treponema pallidum and develop syphilis, a disease with broad symptomatology that, due to the difficulty to eradicate the pathogen from the highly vascularized secondary sites of infection, is ...
core +1 more source
Race and sex differences in ROS production and SOD activity in HUVECs.
PLoS ONE, 2023 Black individuals and men are predisposed to an earlier onset and higher prevalence of hypertension, compared with White individuals and women, respectively.
Sara E Mascone +5 more
doaj +1 more source
Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]
, 2019 PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ +7 more
core +1 more source
Pharmaceutical Biology, 2022 Context Concanavalin A (Con A) exhibited multiple roles in cancer cells. However, the role of Con A in endothelial cells was not reported. Objective Our present study investigated the potential angiogenic role of Con A in endothelial cells and ischaemic ...
Jing-Zhou Li +6 more
doaj +1 more source
Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells [PDF]
, 2018 Several studies have reported endothelial cell (EC) derivation from human induced pluripotent stem cells (hiPSCs). However, few have explored their functional properties in depth with respect to line-to-line and batch-to-batch variability and how they ...
Freund, Christian +6 more
core +3 more sources
Morphology of Biomaterials Affect O-Glycosylation of HUVECs
Journal of Functional Biomaterials, 2022 Biomaterials have been widely used as substitutes for diseased tissue in surgery and have gained great success and attention. At present, the biocompatibility of biomaterials such as PET woven fabrics is often evaluated both in vitro and in vivo. However, the current experimental methods cannot reveal the relationship between material surfaces and cell
Xingyou Hu +5 more
openaire +3 more sources
RNA Biology, 2022 Endothelial cells (ECs) comprise the lumenal lining of all blood vessels and are critical for the functioning of the cardiovascular system. Their phenotypes can be modulated by alternative splicing of RNA to produce distinct protein isoforms.
Madison M. Mehlferber +9 more
doaj +1 more source