Results 41 to 50 of about 121,366 (309)
Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]
, 2019 Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C +4 more
core +2 more sources
MicroRNAs Influence the Migratory Ability of Human Umbilical Vein Endothelial Cells
Genes, 2022 To identify miRNAs that are involved in cell migration in human umbilical vein endothelial cells (HUVECs), we employed RNA sequencing under high glucose incubation and text mining within the databases miRWalk and TargetScanHuman using 83 genes that regulate HUVECs migration. From both databases, 307 predicted miRNAs were retrieved.
Zhaohui Wang +9 more
openaire +2 more sources
Cellular and Molecular Gastroenterology and Hepatology, 2018 Modeling interactions between primary human hepatocytes (PHHs) and primary human liver sinusoidal endothelial cells (LSECs) in vitro can help elucidate human-specific mechanisms underlying liver physiology/disease and drug responses; however, existing ...
Brenton R. Ware +3 more
doaj +1 more source
Expression and Purification of Functional Human Vascular Endothelial Growth Factor-A121; the Most Important Angiogenesis Factor [PDF]
Advanced Pharmaceutical Bulletin, 2014 Purpose: Angiogenesis or formation of new blood vessels is an essential process for tumor growth, invasion and metastasis. Vascular Endothelial Growth Factor (VEGF) and its receptors play an important role in angiogenesis-dependent tumors.
Fatemeh Kazemi-Lomedasht +7 more
doaj +1 more source
Implications of Endothelial Cell-Mediated Dysfunctions in Vasomotor Tone Regulation
Biologics, 2021 Cardiovascular diseases (CVD) constitute the major cause of death worldwide and show a higher prevalence in the adult population. The human umbilical cord consistsof two arteries and one vein, both composed of three tunics.
Carolina Mangana +2 more
doaj +1 more source
The biological properties of OGI surfaces positively act on osteogenic and angiogenic commitment of mesenchymal stem cells [PDF]
, 2017 Osteogenesis process displays a fundamental role during dental implant osteointegration. In the present work, we studied the influence of Osteon Growth Induction (OGI) surface properties on the angiogenic and osteogenic behaviors of ...
Bressan, Eriberto +7 more
core +2 more sources
Drug Design, Development and Therapy, 2021 Jinpeng Wang,1 Yue Wang,2 Yuyi Zhao,2 Jinbin Zhao,2 Beilin Zhang,3 Kun Xu2,4 1Department of Cardiology, The Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 2Department of Nutrition and Food Hygiene, School of ...
Wang J +5 more
doaj
Journal of Pharmacological Sciences, 2008 Phosphatidylinositol (PI), a phospholipid in component of cell membranes, is widely distributed in animals, plants, and microorganisms. Here, we examined in vitro whether PI inhibits the angiogenesis induced by vascular endothelial growth factor-A (VEGF ...
Nozomu Matsunaga +3 more
doaj +1 more source
Isolation of equine endothelial cells and life cell angiogenesis assay [PDF]
, 2014 Arterial or venous thromboses are frequent clinical complications with the risk of fatal progression. Recent studies suggest the disruption of angiogenesis in the course of thrombus resolution as the underlying pathomechanism.
Dietze, Kathrin +5 more
core +1 more source
Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes [PDF]
, 2013 Objective: Inhibitor of apoptosis proteins (IAPs), such as X-linked or cellular IAP 1/2 (XIAP, cIAP1/2), are important regulators of apoptosis. IAP antagonists are currently under clinical investigation as anticancer agents.
Erhardt, Annette +10 more
core +1 more source