Results 91 to 100 of about 128,726 (309)

Human umbilical cord expresses several vasoactive peptides involved in the local regulation of vascular tone: protein and gene expression of Orphanin, Oxytocin, ANP, eNOS and iNOS

Folia Histochemica et Cytobiologica, 2011
Full-term human umbilical cord contains three blood vessels: two arteries coiled around a vein and surrounded by Wharton’s jelly, a mucous tissue with few mesenchymal stromal cells and abundant extracellular matrix.
Aldo Gerbino, Salvatore Provenzano, Maria Buscemi, Annamaria Mauro   +3 more
doaj   +1 more source

High glucose enhances store-operated calcium entry by upregulating ORAI/STIM via calcineurin-NFAT signalling [PDF]

, 2014
© 2014, Springer-Verlag Berlin Heidelberg. Abstract: ORAI and stromal interaction molecule (STIM) are store-operated channel molecules that play essential roles in human physiology through a coupling mechanism of internal Ca 2+ store to Ca 2+ influx ...
Atkin, Stephen L., Ayoola, James, Berglund, Lisa,, Bhandari, Sunil, Chen, Gui-Lan, Daskoulidou, Nikoleta, Gomez, Maria,, Griffin, Steven, Jiang, Hongni, Kotova, Olga,, Lund University., Lund University., Lund University., Xu, Shang-Zhong, Zeng, Bo   +14 more
core   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells [PDF]

Clinics
OBJECTIVES: Hypoxia leads to endothelial cell inflammation, apoptosis, and damage, which plays an important role in the complications associated with ischemic cardiovascular disease.
Xiaohui Zhou, Jing Liu, Siyi Yang, Yanguang Su, Zhipeng Meng, Yuqin Hu   +5 more
doaj   +2 more sources

In-depth proteomics identifies a role for autophagy in controlling reactive oxygen species mediated endothelial permeability [PDF]

, 2016
Endothelial cells (ECs) form the inner layer of blood vessels and physically separate the blood from the surrounding tissue. To support tissues with nutrients and oxygen, the endothelial monolayer is semipermeable.
Anderson, Kurt I., Athineos, Dimitris, Blyth, Karen, Erami Rud Majani, Zahra, Neilson, Lisa, Patella, Francesca, Ryan, Kevin, Zanivan, Sara Rossana   +7 more
core   +10 more sources

Histone deacetylase 2-mediated deacetylation of the Ribonuclease 1 promoter in inflamed human endothelial cells [PDF]

, 2020
Endothelial cells (ECs) function as protective barrier to separate the blood from the surrounding tissue by conducting crucial roles in regulation and maintenance of vascular homeostasis, such as control of vessel permeability or coagulation.
Bedenbender, Katrin
core   +1 more source

Three‐Dimensional Ovary Model to Improve and Study Murine Follicle Growth

Advanced Healthcare Materials, EarlyView.
To develop new methods for fertility preservation in women, novel culture systems for small follicles need to be established. In this work, a poly(ethylene glycol) based scaffold, with appropriate mechanical and bioactive features to support mouse follicle and ovary cell growth is developed, and the formed cell‐follicle interactions are visualized ...
Mira Jacobs, Valon Gllareva, Lukas Moser, Silvia Pravato, Eric Mora Pimentel, Brigitte Leeners, Martin Ehrbar   +6 more
wiley   +1 more source

Efficient Gene Transfer to Human Endothelial Cells Using DNA Complexed to Adenovirus Particles

BioTechniques, 1998
Human endothelial cells have been found to be relatively refractory to various methods of DNA transfection currently in common use. By using a transfection method involving DNA complexed with replication-deficient adenovirus particles, we have shown that
Cora-Jean S. Edgell, David T. Curiel, Ping-Chuan Hu, Henry S. Marr   +3 more
doaj   +1 more source

Effect of cell density on thrombin binding to a specific site on bovine vascular endothelial cells. [PDF]

, 1981
We studied thrombin binding to proliferating and confluent endothelial cells derived from bovine vascular endothelium. [125]thrombin was incubated with nonconfluent or confluent endothelial cells and both the total amount bound and the amount linked in a
Gospodarowicz, D, Isaacs, J, Savion, N, Shuman, MA   +3 more
core  

Insulin Induces Relaxation and Decreases Hydrogen Peroxide-Induced Vasoconstriction in Human Placental Vascular Bed in a Mechanism Mediated by Calcium-Activated Potassium Channels and L-Arginine/Nitric Oxide Pathways [PDF]

, 2016
Insulin induces relaxation in umbilical veins, increasing the expression of human amino acid transporter 1 (hCAT-1) and nitric oxide synthesis (NO) in human umbilical vein endothelial cells (HUVECs). Short-term effects of insulin on vasculature have been
Andrea Saavedra, Astrid Haensgen, Carlos Alonso Escudero, Carlos Alonso Escudero, Coralia Rivas, Cristina Valenzuela, David Alejandro Gallegos Rozas, Eduardo Peña, Emerita Basualto, Juan Carlos Vera, Leandro Zuniga, Lissette Cabrera, Lissette Cabrera, Luis Sobrevia, Luis Sobrevia, Luis Sobrevia, Marcela Cid, Marcelo González, Marcelo González, Mark Wareing, Pamela Careaga, Susana Rojas, Victoria Gallardo   +22 more
core   +3 more sources