Results 281 to 290 of about 128,726 (309)
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Isolation and Culture of Human Umbilical Vein Endothelial Cells
2003The vascular endothelium was, in the past, considered to be relatively pas- sive, merely acting as a filter between the blood and the vessel wall. It is now clear that endothelial cells actively contribute to the maintenance of vascular homeostasis. Endothelial cells synthesize and secrete activators as well as inhibitors of both the coagulation system
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Transcriptome of Angiopoietin 1–Activated Human Umbilical Vein Endothelial Cells
Endothelium, 2007Angiopoietin 1 (Ang-1) is the main ligand for endothelial cell-specific tyrosine kinase (Tie-2) receptors and it promotes migration and proliferation and inhibits apoptosis and vascular leakage. The exact mechanisms through which the Ang-1 exerts these effects remain unclear. The authors exposed human umbilical vein endothelial cells (HUVECs) to Ang-1 (
N A, Abdel-Malak +2 more
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Retinoic acid receptor transcripts in human umbilical vein endothelial cells
Biochemical and Biophysical Research Communications, 1991Human umbilical vein endothelial cells contain high levels of mRNA for the beta-retinoic acid receptor, and very low levels of alpha-retinoic acid receptor transcripts. The cells responded to retinoic acid with a significant induction of tissue transglutaminase expression but no alterations in the expression of beta-retinoic acid receptor transcripts ...
L, Fesus +3 more
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Human umbilical vein endothelial cell culture on heparin‐like microcarriers
Journal of Biomedical Materials Research, 1993AbstractBiospecific functional polymers, i. e., polymers randomly substituted with specific chemical functional groups, were designed to interact with living systems. Interactions between polystyrene sodium sulfonate (PSSO3Na) and insulin secreting RINm5F cells have been previously described.For the sake of comparison, interactions of PSSO3Na with ...
M, Najab-Benhayoun +5 more
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Isolation and Culture of Human Umbilical Vein Endothelial Cells (HUVEC)
Current Protocols in Microbiology, 2007AbstractHuman‐derived endothelial cells can now be routinely harvested from human umbilical veins. Studies with human umbilical vein endothelial cells (HUVEC) have been conducted with cells from passage 2 to 5. It is now also possible to cryopreserve primary and early‐passaged HUVEC for future propagation and for forwarding to an end user by express ...
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Thrombin-induced ATP release from human umbilical vein endothelial cells
American Journal of Physiology-Cell Physiology, 2012ATP and its degradation products play an important role as signaling molecules in the vascular system, and endothelial cells are considered to be an important source of nucleotide release. To investigate the mechanism and physiological significance of endothelial ATP release, we compared different pharmacological stimuli for their ability to evoke ATP
Stefanie, Gödecke +5 more
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Antiapoptotic effect of ouabain on human umbilical vein endothelial cells
Biochemical and Biophysical Research Communications, 2004The present study investigates the effect of ouabain on caspase-3 activation in human umbilical vein endothelial cells (HUVEC). Ouabain (EC(50) 20 nM) reduced caspase-3 activity in HUVEC treated for 24h in a medium deprived of fibroblast growth factor (FGF).
TREVISI, LUCIA +4 more
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SIRT4 Suppresses Inflammatory Responses in Human Umbilical Vein Endothelial Cells
Cardiovascular Toxicology, 2014The most common feature of endothelial dysfunction is endothelial inflammation. A bunch of factors are associated with endothelial dysfunction. These include pro-inflammatory cytokines, cell adhesion molecules, and matrix degrading enzymes. SIRT4, a member of the sirtuin family, is a mitochondrial ADP-ribosyltransferase.
Yu, Tao +6 more
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Enterovirus infection and activation of human umbilical vein endothelial cells
Journal of Medical Virology, 2003AbstractGastrointestinal tract associated lymphoid tissue is considered to be the main replication site for enteroviruses. In order to invade tissues to reach pancreatic islets, cardiac muscles, and other secondary replication sites, the virus has to survive circulation in the blood and find a way to get through endothelial cells. In the present study,
Salla, Saijets +4 more
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