Results 101 to 110 of about 19,992 (185)

Striatal Neuron Excitability Is Regulated by Huntingtin in the Adult Brain. [PDF]

eNeuro
Barron JC, Greenland ML, Carew SJ, Ashrafganjoie F, Hurley EP, Kennedy CM, Nafar F, Moore CS, Parsons MP.   +8 more
europepmc   +1 more source

Lipid Composition Drives Mutant Huntingtin Dimerization and Membrane Association: Insights from Computational Simulations. [PDF]

Molecules
Nicoara C, Criscuolo E, De Cristofaro A, Fezza F, Maccarrone M.   +4 more
europepmc   +1 more source

Data-driven model reveals increased stability of CAG-expanded huntingtin RNA due to MID1 binding. [PDF]

PLoS Comput Biol
Liu Y, Reisbitzer A, Dorešić D, Hasenauer J, Krauß S, Tchumatchenko T.   +5 more
europepmc   +1 more source

Corrigendum: The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function

Frontiers in Molecular Neuroscience, 2017
Wojciech J. Szlachcic, Kalina Wiatr, Marta Trzeciak, Marek Figlerowicz, Maciej Figiel   +4 more
doaj   +1 more source

Genetic suppressor of autophagy defects in huntingtin null cells identified using a mutagenesis screen in Dictyostelium discoideum. [PDF]

BMC Mol Cell Biol
Cuoco L, Gill SE, Francois L, Souders S, DeMasi C, Moore JR, Chain FJJ.   +6 more
europepmc   +1 more source

Molecular features of a Huntington's disease knock-in minipig. [PDF]

Dis Model Mech
Kolesnikova A, Sathasivam K, Tusi SK, Landles C, Osborne GF, Kovalenko M, Gillis T, Kamenná E, Sekáč D, Nguyen DT, Valeková I, Juhás Š, Juhásová J, Levinská B, Baxa M, Motlík J, Klíma J, Howland D, Wheeler VC, Bates GP, Ellederova Z.   +20 more
europepmc   +1 more source

Mutant huntingtin expression in somatostatin-positive interneurons contributes to neurophysiological and behavioral phenotypes in BACHD mice. [PDF]

Dis Model Mech
Fowler JA, Scarduzio M, Pool C, Mahan CD, Gray M.   +4 more
europepmc   +1 more source

AMT-130 gene therapy: a promising disease-modifying approach for Huntington's disease. [PDF]

Ann Med Surg (Lond)
Mwape C, Qureshi AA, Saeed MZ, Fatima A, Jamil A, Mahmood H, Batool A, Khan AM.   +7 more
europepmc   +1 more source

Altered huntingtin−chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease

Disease Models & Mechanisms
Jocelynn R. Pearl, Amol C. Shetty, Jeffrey P. Cantle, Dani E. Bergey, Robert M. Bragg, Sydney R. Coffey, Holly B. Kordasiewicz, Leroy E. Hood, Nathan D. Price, Seth A. Ament, Jeffrey B. Carroll   +10 more
doaj   +1 more source

Epitope-specific antibodies can distinguish between soluble huntingtin exon-1 and its diverse cellular aggregates. [PDF]

J Biol Chem
Lugo J, Xu H, Chen J, Khoshnan A, Langen R.   +4 more
europepmc   +1 more source