Results 131 to 140 of about 28,868 (258)

Huntingtin-mediated axonal transport requires arginine methylation by PRMT6

Cell Reports, 2021
Summary: The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development throughout life. To better understand how HTT mediates axonal transport and why this function is disrupted
Alice Migazzi, Chiara Scaramuzzino, Eric N. Anderson, Debasmita Tripathy, Ivó H. Hernández, Rogan A. Grant, Michela Roccuzzo, Laura Tosatto, Amandine Virlogeux, Chiara Zuccato, Andrea Caricasole, Tamara Ratovitski, Christopher A. Ross, Udai B. Pandey, José J. Lucas, Frédéric Saudou, Maria Pennuto, Manuela Basso   +17 more
doaj  

SH3GL3 Associates with the Huntingtin Exon 1 Protein and Promotes the Formation of Polygln-Containing Protein Aggregates [PDF]

, 1998
Annie Sittler, Stephanie Wälter, Niels Wedemeyer, Renate Hasenbank, Eberhard Scherzinger, Holger Eickhoff, Gillian P. Bates, Hans Lehrach, Erich E. Wanker   +8 more
openalex   +1 more source

α-Synuclein overexpression promotes aggregation of mutant huntingtin [PDF]

, 2000
Robert A. FURLONG, Yolanda NARAIN, Julia RANKIN, Andreas Wyttenbach, David C. Rubinsztein   +4 more
openalex   +2 more sources

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain [PDF]

, 1997
Veronica Colomer, Simone Engelender, Alan H. Sharp, Kui Duan, J.K. Cooper, A. Lanahan, G. L. Lyford, Paul F. Worley, Christopher A. Ross   +8 more
openalex   +1 more source

Huntingtin and mitosis

, 2012
La maladie de Huntington (MH) est une maladie neurodégénérative héréditaire autosomique dominante. Elle résulte d’une expansion anormale de glutamines (polyQ) dans la partie N-terminale de la protéine huntingtine (HTT ; codé par HTT). La MH est caractérisée par la dysfonction et la mort de cellules neuronales dans le cerveau, entraînant l’apparition de
openaire   +1 more source

Expression of Normal and Mutant Huntingtin in the Developing Brain [PDF]

, 1996
Pradeep G. Bhide, Michelle Day, Ellen Sapp, Cordula Schwarz, Ami N. Sheth, Johnny Kim, Anne B. Young, John B. Penney, Jeffrey A. Golden, Neil Aronin, Marian DiFiglia   +10 more
openalex   +1 more source

Avoiding errors in the diagnosis of (CAG)n expansion in the huntingtin gene. [PDF]

, 1997
Carsten Holzmann, Ana Maria Menezes Saecker, Jörg T. Epplen, Olaf Rieß   +3 more
openalex   +1 more source

Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models

Neurobiology of Disease, 2006
Huntington disease (HD) is a devastating neuropsychiatric disease caused by expansion of a trinucleotide repeat (CAG) in the HD gene. Neuropathological changes include the appearance of N-terminal huntingtin fragments, decreased brain weight and ...
Rona K. Graham, Elizabeth J. Slow, Yu Deng, Nagat Bissada, Ge Lu, Jacqueline Pearson, Jacqueline Shehadeh, Blair R. Leavitt, Lynn A. Raymond, Michael R. Hayden   +9 more
doaj  

Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy [PDF]

, 2000
Kimberly B. Kegel, Manho Kim, Ellen Sapp, Charmian McIntyre, José G. Castaño, Neil Aronin, Marian DiFiglia   +6 more
openalex   +1 more source

Analysis of CAG and CCG repeats in Huntingtin gene among HD patients and normal populations of India [PDF]

, 2000
Sreemanta Pramanik, P. Basu, Prasanta K. Gangopadhaya, Krishna K. Sinha, Dilip Kumar Jha, Srish Sinha, Shyamal Kumar Das, Bibek K Maity, Amitava Mukherjee, Sushanta Roychoudhuri, Partha P. Majumder, Nitai P. Bhattacharyya   +11 more
openalex   +1 more source