Results 181 to 190 of about 44,176 (282)

A new hope for patients with Huntington's disease? [PDF]

EClinicalMedicine
eClinicalMedicine.
europepmc   +1 more source

The Molecular Architecture of Neurodegeneration: An Integrative Overview of Convergent Mechanisms. [PDF]

NeuroSci
Aranda-Abreu GE, Rojas-Durán F, Hernández-Aguilar ME, Herrera-Covarrubias D, Tlapa-Monge LR, Mestizo-Gutiérrez SL.   +5 more
europepmc   +1 more source

Polyglutamine Flanking Regions in Huntingtin Highlight Key Structural Intermediates Relevant for Molecular Chaperone Interaction and Huntington's Disease Pathogenesis [PDF]

, 2014
Koning Shen, Barbara Calamini, Donald C. Lo, Judith Frydman   +3 more
openalex   +1 more source

Proteasomal Degradation of Mutant Huntingtin Exon1 Regulates Autophagy. [PDF]

Cells
Folger A, Chen C, Gonzalez P, Owutey SL, Wang Y.   +4 more
europepmc   +1 more source

Regulation of nuclear transport of the transcriptional factor REST improves axon regeneration in peripheral nerves. [PDF]

Mol Med Rep
Suzuki T, Naito K, Kubota D, Ueno Y, Negishi-Koga T, Yamamoto Y, Kawakita S, Imazu N, Kawamura K, Hattori N, Ishijima M.   +10 more
europepmc   +1 more source

A046 Uncovering the pathobiology of polyglutamine-expanded huntingtin in Huntington’s disease [PDF]

Erich E. Wanker
openalex   +1 more source

Huntingtin and mitosis

, 2012
La maladie de Huntington (MH) est une maladie neurodégénérative héréditaire autosomique dominante. Elle résulte d’une expansion anormale de glutamines (polyQ) dans la partie N-terminale de la protéine huntingtine (HTT ; codé par HTT). La MH est caractérisée par la dysfonction et la mort de cellules neuronales dans le cerveau, entraînant l’apparition de
openaire   +1 more source

Altered huntingtin−chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease

Disease Models & Mechanisms
Jocelynn R. Pearl, Amol C. Shetty, Jeffrey P. Cantle, Dani E. Bergey, Robert M. Bragg, Sydney R. Coffey, Holly B. Kordasiewicz, Leroy E. Hood, Nathan D. Price, Seth A. Ament, Jeffrey B. Carroll   +10 more
doaj   +1 more source

Brain-Derived Neurotrophic Factor Trafficking via the Regulated Secretory Pathway: Mechanisms and Disease Implications. [PDF]

Mol Neurobiol
Ewell SN.
europepmc   +1 more source

Fibrilpaints as a tool to bind and modulate huntingtin amyloids

Françoise A. Dekker, Emile van Weert, Alfred C.O. Vertegaal, Assaf Friedler, Stefan Rüdiger   +4 more
openalex   +1 more source