Results 221 to 230 of about 25,505 (239)

Loss of normal huntingtin function: new developments in Huntington's disease research

Trends in Neurosciences, 2001
Elena Cattaneo, Dorotea Rigamonti, Chiara Zuccato   +2 more
exaly  

Huntingtin inhibits caspase-3 activation

EMBO Journal, 2006
Blair R Leavitt, Jeremy M Van Raamsdonk, Ioannis Dragatsis   +2 more
exaly  

Nature and cause of mitochondrial dysfunction in Huntington’s disease: focusing on huntingtin and the striatum

Journal of Neurochemistry, 2010
Jorge M A Oliveira
exaly  

Huntingtin toxicity

Trends in Molecular Medicine, 2001
openaire   +1 more source

A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation

Molecular Cell, 2018
Frédérique Rau, Rickie Patani, Alan R Lowe   +2 more
exaly  

Huntingtin: a single bait hooks many species

Current Opinion in Neurobiology, 1998
James F Gusella, Marcy E Macdonald, M E Macdonald   +2 more
exaly  

Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction

Biochemical and Biophysical Research Communications, 2006
Anand Goswami, Amit Mishra, Nobuyuki Nukina   +2 more
exaly  

Imaging mutant huntingtin in vivo

Nature Reviews Drug Discovery, 2022
openaire   +2 more sources

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation

Proceedings of the National Academy of Sciences of the United States of America, 2017
Margherita Verani, Paola Martufi, Anass Chiki   +2 more
exaly  

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington’s disease pathology

Proceedings of the National Academy of Sciences of the United States of America, 1999
Eberhard Scherzinger, Annie Sittler, Rudi Lurz   +2 more
exaly