Results 211 to 220 of about 40,748 (225)

A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation

Molecular Cell, 2018
Frederique Rau, Rickie Patani, Alan R Lowe   +2 more
exaly  

Huntingtin: a single bait hooks many species

Current Opinion in Neurobiology, 1998
James F Gusella
exaly  

Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction

Biochemical and Biophysical Research Communications, 2006
Amit Mishra, Nobuyuki Nukina, Nihar R Jana   +2 more
exaly  

Imaging mutant huntingtin in vivo

Nature Reviews Drug Discovery, 2022
openaire   +2 more sources

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation

Proceedings of the National Academy of Sciences of the United States of America, 2017
Marta Cherubini, Sílvia Ginés, Elena Cattaneo   +2 more
exaly  

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington’s disease pathology

Proceedings of the National Academy of Sciences of the United States of America, 1999
Annie Sittler, Gillian P Bates
exaly  

Depletion of wild-type huntingtin in mouse models of neurologic diseases

Journal of Neurochemistry, 2003
Blair R Leavitt, Mdcm, Elena Cattaneo, Michael R Hayden   +2 more
exaly  

The Benefits of Huntingtin

Science, 2001
openaire   +1 more source

Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor

Neurobiology of Disease, 2019
Chelsy R Eddings, Nicolas Arbez, Sergey Akimov   +2 more
exaly  

Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model

Journal of Neurochemistry, 2011
Paolo Paganetti
exaly