Results 91 to 100 of about 19,163 (188)

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

The Chemical Record, Volume 26, Issue 8, August 2026.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato, Kazuki Miura, Juki Nakao, Hiroyuki Nakamura   +3 more
wiley   +1 more source

Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40. [PDF]

Structure, 2023
Alteen MG, Deme JC, Alvarez CP, Loppnau P, Hutchinson A, Seitova A, Chandrasekaran R, Silva Ramos E, Secker C, Alqazzaz M, Wanker EE, Lea SM, Arrowsmith CH, Harding RJ.   +13 more
europepmc   +1 more source

Elucidating the Influence of Lipid Composition on Bilayer Perturbations Induced by the N-terminal Region of the Huntingtin Protein. [PDF]

Biophysica, 2023
Gamage YI, Pan J.
europepmc   +1 more source

Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease

Molecular Brain, 2009
Background Huntington's disease (HD) is an inherited neurogenerative disease caused by an abnormal expansion of glutamine repeats in the huntingtin protein.
Pineda Jose R, Pardo Raúl, Zala Diana, Yu Hua, Humbert Sandrine, Saudou Frédéric   +5 more
doaj   +1 more source

Detection of antibodies against the huntingtin protein in human plasma. [PDF]

Cell Mol Life Sci, 2023
Denis HL, Alpaugh M, Alvarez CP, Fenyi A, Barker RA, Chouinard S, Arrowsmith CH, Melki R, Labib R, Harding RJ, Cicchetti F.   +10 more
europepmc   +1 more source

Salivary Huntingtin protein is uniquely associated with clinical features of Huntington's disease. [PDF]

Sci Rep, 2023
Parkin GM, Corey-Bloom J, Snell C, Smith H, Laurenza A, Daldin M, Bresciani A, Thomas EA.   +7 more
europepmc   +1 more source

Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates. [PDF]

Mol Biol Cell, 2022
Bae D, Jones RE, Piscopo KM, Tyagi M, Shepherd JD, Hollien J.   +5 more
europepmc   +1 more source

Comparative molecular dynamics simulations of pathogenic and non-pathogenic huntingtin protein monomers and dimers. [PDF]

Front Mol Biosci, 2023
Khaled M, Strodel B, Sayyed-Ahmad A.
europepmc   +1 more source

Quantifying mutant huntingtin protein in human cerebrospinal fluid to support the development of huntingtin-lowering therapies. [PDF]

Sci Rep, 2023
Vauleon S, Schutz K, Massonnet B, Gruben N, Manchester M, Buehler A, Schick E, Boak L, Hawellek DJ.   +8 more
europepmc   +1 more source

The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein. [PDF]

Hum Mol Genet, 2023
Bonavita R, Scerra G, Di Martino R, Nuzzo S, Polishchuk E, Di Gennaro M, Williams SV, Caporaso MG, Caiazza C, Polishchuk R, D'Agostino M, Fleming A, Renna M.   +12 more
europepmc   +1 more source