Results 81 to 90 of about 6,542,668 (155)

Detection of antibodies against the huntingtin protein in human plasma. [PDF]

Cell Mol Life Sci, 2023
Denis HL, Alpaugh M, Alvarez CP, Fenyi A, Barker RA, Chouinard S, Arrowsmith CH, Melki R, Labib R, Harding RJ, Cicchetti F.   +10 more
europepmc   +1 more source

Salivary Huntingtin protein is uniquely associated with clinical features of Huntington's disease. [PDF]

Sci Rep, 2023
Parkin GM, Corey-Bloom J, Snell C, Smith H, Laurenza A, Daldin M, Bresciani A, Thomas EA.   +7 more
europepmc   +1 more source

Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates. [PDF]

Mol Biol Cell, 2022
Bae D, Jones RE, Piscopo KM, Tyagi M, Shepherd JD, Hollien J.   +5 more
europepmc   +1 more source

Comparative molecular dynamics simulations of pathogenic and non-pathogenic huntingtin protein monomers and dimers. [PDF]

Front Mol Biosci, 2023
Khaled M, Strodel B, Sayyed-Ahmad A.
europepmc   +1 more source

Quantifying mutant huntingtin protein in human cerebrospinal fluid to support the development of huntingtin-lowering therapies. [PDF]

Sci Rep, 2023
Vauleon S, Schutz K, Massonnet B, Gruben N, Manchester M, Buehler A, Schick E, Boak L, Hawellek DJ.   +8 more
europepmc   +1 more source

The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein. [PDF]

Hum Mol Genet, 2023
Bonavita R, Scerra G, Di Martino R, Nuzzo S, Polishchuk E, Di Gennaro M, Williams SV, Caporaso MG, Caiazza C, Polishchuk R, D'Agostino M, Fleming A, Renna M.   +12 more
europepmc   +1 more source

Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. [PDF]

Cell Syst, 2022
Greco TM, Secker C, Ramos ES, Federspiel JD, Liu JP, Perez AM, Al-Ramahi I, Cantle JP, Carroll JB, Botas J, Zeitlin SO, Wanker EE, Cristea IM.   +12 more
europepmc   +1 more source

Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression. [PDF]

Pharmaceutics, 2021
Chen XQ, Barrero CA, Vasquez-Del Carpio R, Reddy EP, Fecchio C, Merali S, Deglincerti A, Fang C, Rogers J, Maccecchini ML.   +9 more
europepmc   +1 more source

Siah-1-interacting protein regulates mutated huntingtin protein aggregation in Huntington's disease models. [PDF]

Cell Biosci, 2022
Latoszek E, Wiweger M, Ludwiczak J, Dunin-Horkawicz S, Kuznicki J, Czeredys M.   +5 more
europepmc   +1 more source

Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide. [PDF]

Proc Natl Acad Sci U S A, 2022
Song H, Wang C, Zhu C, Wang Z, Yang H, Wu P, Cui X, Botas J, Dang Y, Ding Y, Fei Y, Lu B.   +11 more
europepmc   +1 more source