Results 161 to 170 of about 5,553,804 (280)

SH3GL3 Associates with the Huntingtin Exon 1 Protein and Promotes the Formation of Polygln-Containing Protein Aggregates [PDF]

, 1998
Annie Sittler, Stephanie Wälter, Niels Wedemeyer, Renate Hasenbank, Eberhard Scherzinger, Holger Eickhoff, Gillian P. Bates, Hans Lehrach, Erich E. Wanker   +8 more
openalex   +1 more source

Cardiac dysfunction in the R6/2 mouse model of Huntington’s disease

Neurobiology of Disease, 2007
Recent evidence suggests that mutant huntingtin protein-induced energetic perturbations contribute to neuronal dysfunction in Huntington’s disease (HD). Given the ubiquitous expression of huntingtin, other cell types with high energetic burden may be at ...
Michael J. Mihm, Deborah M. Amann, Brandon L. Schanbacher, Ruth A. Altschuld, John Anthony Bauer, Kari R. Hoyt   +5 more
doaj  

Salivary Huntingtin protein is uniquely associated with clinical features of Huntington's disease. [PDF]

Sci Rep, 2023
Parkin GM, Corey-Bloom J, Snell C, Smith H, Laurenza A, Daldin M, Bresciani A, Thomas EA.   +7 more
europepmc   +1 more source

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles [PDF]

, 2000
Paige Hilditch-Maguire
openalex   +1 more source

Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates. [PDF]

Mol Biol Cell, 2022
Bae D, Jones RE, Piscopo KM, Tyagi M, Shepherd JD, Hollien J.   +5 more
europepmc   +1 more source

Huntingtin Interacting Protein 1 Induces Apoptosis via a Novel Caspase-dependent Death Effector Domain [PDF]

, 2000
Abigail S. Hackam, Ayman S. Yassa, Roshni R. Singaraja, Martina Metzler, Claire-Anne Gutekunst, Lu Gan, Simon C. Warby, Cheryl L. Wellington, John P. Vaillancourt, Nansheng Chen, François G. Gervais, Lynn A. Raymond, Donald W. Nicholson, Michael R. Hayden   +13 more
openalex   +1 more source

Comparative molecular dynamics simulations of pathogenic and non-pathogenic huntingtin protein monomers and dimers. [PDF]

Front Mol Biosci, 2023
Khaled M, Strodel B, Sayyed-Ahmad A.
europepmc   +1 more source

Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins [PDF]

, 2000
Chi Wai Eric So, MH Sham, Sze Lun CHEW, Ngai Cheung, C K So, Sookja Kim Chung, Carlos Caldas, Markus Wiedemann, Li Chong Chan   +8 more
openalex   +1 more source

Accumulation of Mutant Huntingtin Fragments in Aggresome-like Inclusion Bodies as a Result of Insufficient Protein Degradation [PDF]

, 2001
Stephanie Waelter, Annett Boeddrich, Rudi Lurz, Eberhard Scherzinger, Gerhild Lueder, Hans Lehrach, Erich E. Wanker   +6 more
openalex   +1 more source

The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein. [PDF]

Hum Mol Genet, 2023
Bonavita R, Scerra G, Di Martino R, Nuzzo S, Polishchuk E, Di Gennaro M, Williams SV, Caporaso MG, Caiazza C, Polishchuk R, D'Agostino M, Fleming A, Renna M.   +12 more
europepmc   +1 more source