Results 161 to 170 of about 19,301 (228)

One‐Pot Semisynthesis of Exon 1 of the Huntingtin Protein: New Tools for Elucidating the Role of Posttranslational Modifications in the Pathogenesis of Huntington’s Disease

, 2014
Annalisa Ansaloni, Zheming Wang, Jae Sun Jeong, Francesco Simone Ruggeri, Giovanni Dietler, Hilal A. Lashuel   +5 more
openalex   +2 more sources

Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease. [PDF]

Neurosci Bull, 2019
Yang W, Xie J, Qiang Q, Li L, Lin X, Ren Y, Ren W, Liu Q, Zhou G, Wei W, Saiyin H, Ma L.   +11 more
europepmc   +1 more source

Potential function for the Huntingtin protein as a scaffold for selective autophagy [PDF]

, 2014
Joseph Ochaba, Tamás Lukácsovich, George Csikós, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice Lau, Sylvia Y. Yeung, Sandrine Humbert, Frédéric Saudou, Daniel J. Klionsky, Steven Finkbeiner, Scott Zeitlin, Joan Marsh, David E. Housman, Leslie M. Thompson, Joan S. Steffan   +17 more
openalex   +1 more source

Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay. [PDF]

eNeuro, 2018
Baldo B, Sajjad MU, Cheong RY, Bigarreau J, Vijayvargia R, McLean C, Perrier AL, Seong IS, Halliday G, Petersén Å, Kirik D.   +10 more
europepmc   +1 more source

Quantification of huntingtin protein species in Huntington's disease patient leukocytes using optimised electrochemiluminescence immunoassays. [PDF]

PLoS One, 2017
Hensman Moss DJ, Robertson N, Farmer R, Scahill RI, Haider S, Tessari MA, Flynn G, Fischer DF, Wild EJ, Macdonald D, Tabrizi SJ.   +10 more
europepmc   +1 more source

Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin [PDF]

Hyun-Ju Cho, Jeonghyun Oh, Christy Catherine, Eun Seon Kim, Kwang Wook Min, Mijin Kim, Hyojin Kim, Hae Chan Jeong, Seung Hae Ahn, Nataliia Lukianenko, Hyeon Seok Bak, Sungsu Lim, Yun Kyung Kim, Ho Min Kim, Sung Bae Lee   +14 more
openalex   +1 more source

Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation. [PDF]

Proc Natl Acad Sci U S A, 2017
Cariulo C, Azzollini L, Verani M, Martufi P, Boggio R, Chiki A, Deguire SM, Cherubini M, Gines S, Marsh JL, Conforti P, Cattaneo E, Santimone I, Squitieri F, Lashuel HA, Petricca L, Caricasole A.   +16 more
europepmc   +1 more source

Juvenile Huntington's Disease Skin Fibroblasts Respond with Elevated Parkin Level and Increased Proteasome Activity as a Potential Mechanism to Counterbalance the Pathological Consequences of Mutant Huntingtin Protein. [PDF]

Int J Mol Sci, 2019
Aladdin A, Király R, Boto P, Regdon Z, Tar K.   +4 more
europepmc   +1 more source

Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease

, 2018
Lauren M. Byrne, Filipe B. Rodrigues, Eileanoir B. Johnson, P. A. Wijeratne, Enrico De Vita, Daniel C. Alexander, Giuseppe Palermo, Christian Czech, Scott Schobel, Rachael I. Scahill, Amanda Heslegrave, Henrik Zetterberg, Edward J. Wild   +12 more
openalex   +2 more sources

ROS-Specific Huntingtin Interactions: Summary of PAR binding for different huntingtin protein preps

, 2019
Tamara Maiuri, Ray Truant
openalex   +2 more sources