Results 111 to 120 of about 10,466,444 (219)

The differential diagnosis of Huntington's disease-like syndromes: 'red flags' for the clinician [PDF]

, 2013
A growing number of progressive heredodegenerative conditions mimic the presentation of Huntington's disease (HD). Differentiating among these HD-like syndromes is necessary when a patient with a combination of movement disorders, cognitive decline ...
Bhatia, KP, Martino, D, Stamelou, M
core  

Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease

Frontiers in Neuroscience, 2018
In recent years, several important advances have been made in our understanding of the pathways that lead to cell dysfunction and death in Parkinson's disease (PD) and Huntington's disease (HD).
Sandra Franco-Iborra, M. Vila, C. Perier
semanticscholar   +1 more source

Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration. [PDF]

, 2019
Current approaches for dynamic profiling of single cells rely on dissociated cultures, which lack important biological features existing in tissues. Organotypic slice cultures preserve aspects of structural and synaptic organisation within the brain and ...
Barch, Mariya, Campioni, Matthew, Epstein, Irina, Finkbeiner, Steven, Javaherian, Ashkan, Linsley, Jeremy W, Mount, Elliot, Nowakowski, Tomasz J, Oza, Viral, Samsi, Siddharth, Schmunk, Galina, Tripathi, Atmiyata   +11 more
core  

Consolidation deficits in episodic memory define distinct clinical and neurodegenerative profiles in Huntington’s disease

NeuroImage: Clinical
Background: Huntington’s disease (HD) is primarily associated with executive dysfunction, but episodic memory impairment is also present. Traditionally, these memory deficits have been attributed to retrieval difficulties linked to fronto-striatal ...
Saul Martinez-Horta, Angela Quevedo-García, Arnau Puig-Davi, Frederic Sampedro, Javier Oltra-Cucarella, Jesús Pérez-Pérez, Carla Franch-Martí, Gonzalo Olmedo-Saura, Elisa Rivas-Asensio, Anna Vazquez-Oliver, Laura Pérez-Carasol, Andrea Horta-Barba, Javier Pagonabarraga, Jaime Kulisevsky   +13 more
doaj   +1 more source

Fused kernel-spline smoothing for repeatedly measured outcomes in a generalized partially linear model with functional single index

, 2015
We propose a generalized partially linear functional single index risk score model for repeatedly measured outcomes where the index itself is a function of time.
Jiang, Fei, Ma, Yanyuan, Wang, Yuanjia
core   +1 more source

Therapeutic advances in neural regeneration for Huntington's disease

Neural Regeneration Research
Huntington's disease is a neurodegenerative disease caused by the expansion mutation of a cytosine-adenine-guanine triplet in the exon 1 of the HTT gene which is responsible for the production of the huntingtin (Htt) protein. In physiological conditions,
Francesco D'Egidio, Vanessa Castelli, Giorgia Lombardozzi, Fabrizio Ammannito, Annamaria Cimini, Michele d'Angelo   +5 more
doaj   +1 more source

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Cell, 1993
M. MacDonald, C. Ambrose, M. Duyao, R. Myers, Carol S. Lin, L. Srinidhi, G. Barnes, Sherryl A. M. Taylor, M. James, Nicolet Groot, Heather MacFarlane, B. Jenkins, M. Anderson, N. Wexler, J. Gusella, G. Bates, S. Baxendale, H. Hummerich, S. Kirby, M. North, S. Youngman, R. Mott, Günther Zehetner, Z. Sedlacek, A. Poustka, A. Frischauf, H. Lehrach, A. Buckler, D. Church, L. Doucette-Stamm, M. O’Donovan, Laura Riba-Ramírez, Manish S. Shah, V. Stanton, S. Strobel, K. Draths, Jennifer L. Wales, P. Dervan, D. Housman, M. Altherr, R. Shiang, L. Thompson, T. Fielder, J. Wasmuth, D. Tagle, J. Valdes, Lon Elmer, M. Allard, L. Castilla, M. Swaroop, K. Blanchard, F. Collins, R. Snell, T. Holloway, Kathleen Gillespie, N. Datson, D. Shaw, P. Harper   +57 more
semanticscholar   +1 more source

Neuropathological Classification of Huntington's Disease

Journal of Neuropathology and Experimental Neurology, 1985
J. Vonsattel, R. Myers, Thomas J. Stevens, R. Ferrante, E. Bird, E. Richardson   +5 more
semanticscholar   +1 more source

2008 Progress Report on Brain Research [PDF]

, 2008
Highlights new research on various disorders, nervous system injuries, neuroethics, neuroimmunology, pain, sense and body function, stem cells and neurogenesis, and thought and memory.
Eve Marder, Mahlon R. DeLong, Michael S. Gazzaniga, Thomas Wichmann   +3 more
core  

Huntington's disease: a clinical review

European Journal of Neurology, 2018
P. McColgan, S. Tabrizi
semanticscholar   +1 more source