More than 185 CAG repeats: a point of no return in Huntington’s disease biology [PDF]
Jillian Belgrad, Anastasia Khvorova
openalex +1 more source
Genetic cooperativity in multi-layer networks implicates cell survival and senescence in the striatum of Huntington’s disease mice synchronous to symptoms [PDF]
, 2019 Erwan Bigan +9 more
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Reduced Dopamine Transporter Uptake in Dentatorubral‐Pallidoluysian Atrophy
Movement Disorders Clinical Practice, EarlyView.
Kei Okuba +3 more
wiley +1 more source
Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic
Small, EarlyView.Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi +11 more
wiley +1 more source
Advances in cholesterol and lipoproteins detection for healthcare: A review
VIEW, EarlyView.Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta +7 more
wiley +1 more source
Histone methylation in Huntington’s disease: are bivalent promoters the critical targets?
, 2018 László Bodai, Nóra Zsindely
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In Vitro Hemocompatibility of the BiVACOR Total Artificial Heart in Continuous and Pulsatile Flow
Artificial Organs, EarlyView.BiVACOR's total artificial heart generates remarkably similar hemocompatibility when operated with a pulse or during continuous flow. Under both conditions, hemolysis and von Willebrand Factor multimers were similar to a commercial reference device after 6 h in vitro evaluation.
Antony P. McNamee +6 more
wiley +1 more source
Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People
Bioethics, EarlyView.ABSTRACT Genome editing in human embryos could raise new ethical issues by changing future people's narrative and numerical identity. Most philosophers agree that some genetic modifications would have larger effects on identity than others, but they disagree on what criteria might explain these differences and have not supported their claims ...
Derek So, Yann Joly, Robert Sladek
wiley +1 more source
Life Without Hope? Huntington\u27s Disease and Genetic Futurity [PDF]
, 2013 Canavan, Gerry
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H038 Health and welfare lasting power of attorneyin Huntington’s disease patients across the west midlands: an audit [PDF]
Ameera Abdullahi, Hugh Rickards
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