Results 201 to 210 of about 10,552,439 (323)

Mapping the Young‐Onset Dementia Research in the Asia‐Pacific Region: A Scoping Review

Asia-Pacific Psychiatry, Volume 18, Issue 3, September 2026.
ABSTRACT Young‐onset dementia (YOD), with symptom onset before 65, is an area of increasing public health importance. YOD research in Asia‐Pacific remains under‐represented in the global YOD research landscape. This scoping review aimed to comprehensively map the existing YOD literature from Asia‐Pacific and provide an overview of the research topics ...
Gia Tan, Gary Cheung, Samantha M. Loi, Etuini Ma'u, Campbell Le Heron, Monica Cations, Nick Garrett, Megan Eustace, So Young Moon, Eun‐Joo Kim, Kok Pin Ng, Adeline S. L. Ng, Huali Wang, Isabelle Burke, Kenny Ong, Brigid Ryan   +15 more
wiley   +1 more source

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.

Proceedings of the National Academy of Sciences of the United States of America, 2000
J. Steffan, A. Kazantsev, O. Spasic-Boskovic, Marilee Greenwald, Ya-zhen Zhu, H. Göhler, E. Wanker, G. Bates, D. Housman, L. Thompson   +9 more
semanticscholar   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Targeting UCHL3 attenuates pathological markers in neuronal models of Huntington's disease. [PDF]

Brain
Ishtayeh H, Battistoni E, Pochtar S, McHugh TLM, Tshilenge KT, Rossmiller B, Amer-Sarsour F, Berdichevsky Y, Muchtar N, Weil M, Ellerby LM, Ashkenazi A.   +11 more
europepmc   +1 more source

The Recommendation Paradox: Perspectives on Genetic Testing in Huntington's Disease Families

Journal of Genetic Counseling, Volume 35, Issue 4, August 2026.
ABSTRACT Huntington's disease (HD) families face complex decisions about predictive genetic testing and reproductive options, including preimplantation genetic testing (PGT), and particularly PGT for Monogenic Disorders (PGT‐M). We examined attitudes toward genetic testing and reproductive options across affected groups within HD families (e.g., people
Noit Inbar, Achinoam Socher, Aya Bar David, Penina Ponger, Nurit Omer, Adi Reches, Yael Manor, Tanya Gurevich   +7 more
wiley   +1 more source

Metabolic reprogramming is critical to microglial activation in Huntington's disease. [PDF]

JCI Insight
Jauhari A, Monek AC, Abakumova OS, Singh T, Singh S, Wang X, Clise CS, Carlisle DL, Friedlander RM.   +8 more
europepmc   +1 more source

Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies.

Cold Spring Harbor Perspectives in Medicine, 2017
M. Jimenez-Sanchez, F. Licitra, B. Underwood, D. Rubinsztein   +3 more
semanticscholar   +1 more source

Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies

Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley   +1 more source

Imaging Venous Transit Time and Blood–Brain Barrier Permeability of the Deep Brain

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 809-816, August 2026.
ABSTRACT Purpose Imaging of venous vessels with advanced pulse sequences allows the assessment of important hemodynamic parameters. Previous work has measured venous transit time (VTT) and blood–brain barrier (BBB) water permeability in cortical tissue.
Wen Shi, Jie Song, Jiani Wu, Yifan Gou, Zhiyi Hu, Vivek Yedavalli, Zixuan Lin, Hanzhang Lu   +7 more
wiley   +1 more source

Modifying Neuropsychiatric and Motor Trajectories in Huntington's Disease Through an Integrated Neurobehavioral Clinic Model. [PDF]

Neuropsychiatr Dis Treat
Khan S, Velez Figueroa L, Selvadurai C, Deshpande AR, Najmivarzaneh F, Lindbergh CA.   +5 more
europepmc   +1 more source