Results 201 to 210 of about 4,904,701 (256)
Understanding Energy Expenditure: An Approach to Improving Activities of Daily Living in Huntington's Disease. [PDF]
Simón-Vicente L +6 more
europepmc +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
ABSTRACT Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor dysfunction, psychiatric disturbances, and cognitive decline. The onset of HD is marked by severe motor impairment, which may be predicted by prior cognitive decline and, in turn, exacerbate cognitive deficits. Clinical data, however, are often
Yue Zhan, Cheng Zheng, Ying Zhang
wiley +1 more source
miR-196a reduces mutant Huntingtin aggregates by Rad23b-mediated degradation in Huntington's disease. [PDF]
Tung CW +6 more
europepmc +1 more source
In ‘The adult Aedes aegypti microbiota is robust to infection with the microsporidian parasite Edhazardia aedis’, Dom Magistrado and Sarah M. Short* use high‐throughput 16S amplicon sequencing to reveal that in contrast to a multitude of other bacterial, viral, and microsporidian pathogens, infection with the microsporidian pathogen E.
Dom Magistrado, Sarah M. Short
wiley +1 more source
ABSTRACT Aim The Na,K‐ATPase is important for energy demanding cellular processes, including essential components of substrate metabolism and metabolic flexibility. Mice heterozygous for the hemiplegic migraine‐related mutation, G301R, of the Na,K‐ATPase α2 isoform (α2+/G301R) demonstrated altered metabolism in the heart.
Christian Staehr +11 more
wiley +1 more source

