Results 11 to 20 of about 2,879 (206)

Huperzia quadrifariata and Huperzia reflexa alkaloids inhibit acetylcholinesterase activity in vivo in mice brain

open access: bronzePhytomedicine, 2012
Huperzine A, a Lycopodium alkaloid produced by Chinese folk herb Huperzia serrata (Lycopodiaceae), has been shown to be a promising agent for the treatment of Alzheimer's disease due to its potent acetylcholinesterase (AChE) activity, as well its efficacy in the treatment of memory of aged patients. Thus, the effects of two Huperzia species of habitats
Eduardo Luis Konrath   +7 more
openalex   +5 more sources

Diversity of endophytic fungal community in Huperzia serrata from different ecological areas and their correlation with Hup A content. [PDF]

open access: yesBMC Microbiol, 2022
Huperzine A (Hup A) has attracted considerable attention as an effective therapeutic candidate drug used to treat Alzheimer’s disease. Whereas, the production of Hup A from wild plants faced a major challenge, which is the wild Huperzia Serrata harbor a ...
Pang B   +10 more
europepmc   +2 more sources

Comprehensive relative quantitative metabolomics analysis of lycopodium alkaloids in different tissues of Huperzia serrata

open access: goldSynthetic and Systems Biotechnology, 2018
Qian ceng Ta, the whole plant of Huperzia serrata, is an important landscape and medicinal herbs and contains abundant bioactive lycopodium alkaloids. Although the structures of more than 100 lycopodium alkaloids in Huperzia serrata have been isolated ...
Shiwen Wu, Zhen Fan, Youli Xiao
doaj   +2 more sources

New PKS/NRPS Tenuazamines A-H from the Endophytic Fungus Alternaria alternata FL7 Isolated from Huperzia serrata. [PDF]

open access: yesJ Fungi (Basel)
In this paper, we present a novel class of hybrid polyketides, tenuazamines A–H (1–8), which exhibit a unique tautomeric equilibrium from Alternaria alternata FL7.
Zhang H   +8 more
europepmc   +2 more sources

Huperzia crassifolia (Lycopodiaceae), a new species from China based on morphological characters and molecular evidence [PDF]

open access: yesPhytoKeys
A new species of the firmoss from China, Huperzia crassifolia sp. nov., is described and illustrated based on morphological characters and molecular evidence. The new species resembles species associated with the H.
Zhi-You Guo   +6 more
doaj   +4 more sources

In Vitro Propagation, Huperzine A Content and Antioxidant Activity of Three Genotypic Huperzia serrata [PDF]

open access: goldPlants, 2021
Huperzia serrata is a traditional herb and endangered Chinese medicinal material, which has attracted much attention due to its production of Huperzine A (HupA). In vitro propagation of H.
Yan Yang   +6 more
openalex   +2 more sources

Reference gene selection for real‐time quantitative PCR assays in different tissues of Huperzia serrata based on full‐length transcriptome sequencing

open access: goldPlant Direct, 2021
Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu   +5 more
doaj   +2 more sources

Huperzia serrata Extract ‘NSP01’ With Neuroprotective Effects-Potential Synergies of Huperzine A and Polyphenols

open access: yesFrontiers in Pharmacology, 2021
Huperzia serrata (Thunb.) Trevis is widely used in traditional asiatic medicine to treat many central disorders including, schizophrenia, cognitive dysfunction, and dementia. The major alkaloid, Huperzine A (HA), of H. serrata is a well-known competitive
N. Callizot   +6 more
doaj   +2 more sources

A Novel Way for Propagation of Huperzia squarrosa (G. Forst.) Trev.

open access: greenNotulae Scientia Biologicae, 2012
Huperzia squarrosa (G. Forst.) Trev. is an endangered epiphytic fern ally with economical, traditional and horticultural interest. It posses various alkaloids like huperzine, huperzinine, lycoporine and carina-tumine which are responsible for its ...
Sanatombi Devi YUMKHAM   +1 more
doaj   +4 more sources

Extended release huperzine for the treatment of idiopathic epilepsy in dogs – a Case Report [PDF]

open access: yesFrontiers in Veterinary Science
Huperzine is a naturally occurring alkaloid derived from the Chinese clubmoss Huperzia serrata. It is a potent acetylcholinesterase inhibitor, among other properties, and has demonstrated protection against induced seizures in a mouse model of Dravet’s ...
Kylie L. Grant, Sam N. Long
doaj   +2 more sources

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