Results 121 to 130 of about 1,632 (162)

Hupertimines A–E, Fawcettimine‐Type Lycopodium Alkaloids from Huperzia serrata

Chemistry & Biodiversity, 2022
AbstractFive new fawcettimine‐type Lycopodium alkaloids, hupertimines A–E (1–5), were discovered from the whole plant of Huperzia serrata, along with two known alkaloids, 8α‐hydroxyphlegmariurine B (6) and 8β‐hydroxyphlegmariurine B (7). The structures of 1–7 were identified through HR‐MS, IR, 1H, 13C, and 2D NMR, and single‐crystal X‐ray diffraction ...
Zhen-Tao, Deng, Yu-Chen, Liu, Qin-Feng, Zhu, Shuai, Jiang, Xing-De, Wu, Qin-Shi, Zhao   +5 more
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Lycopodium Alkaloids from Huperzia serrata and Their Anti‐acetylcholinesterase Activities

Chemistry & Biodiversity, 2023
AbstractOne new fawcettimine‐type alkaloid (1), one new miscellaneous‐type alkaloid (2), four new lycodine‐type alkaloids (3–6), and eight known ones (7–14) were isolated from the whole plants of Huperzia serrata. Their structures and absolute configurations were elucidated based on spectroscopic data, X‐ray diffraction, ECD calculation and Mosher's ...
Wen Li, Hui‐Hui Zhu, Xi Shen, Jin‐Lin Tan, Qing Tang, Zhi‐Peng Ling, Hai‐Yue Zhao, Qiang Lin, Hui Sun, Hai‐Peng Zhang, Yao‐Lan Li, Guo‐Cai Wang, Yu‐Bo Zhang   +12 more
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Two New Lycopodine Alkaloids from Huperzia serrata

Helvetica Chimica Acta, 2010
AbstractTwo new lycopodine alkaloids, (12β)‐12‐hydroxyhuperzine G (1) and (5β,6β,15α)‐15‐methyllycopodane‐5,6‐diol (2), were isolated from the whole plants of Huperzia serrata, together with six known compounds, huperzines A, B, and G, phlegmariurine B, (8β)‐8‐hydroxyphlegmariurine B, and lycoposerramine D. Their structures were elucidated on the basis
Jinhe Jiang, Ying Liu, Kang Min, Bi Jing, Liqin Wang, Yan Zhang, Yegao Chen   +6 more
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Huperzine P, a novel Lycopodium alkaloid from Huperzia serrata

Tetrahedron Letters, 2000
Abstract Huperzine P (1), a new irregular fawcettimine-type Lycopodium alkaloid, was isolated from Huperzia serrata and the absolute stereostructure was established by 2D NMR and X-ray crystallographic analysis.
Chang-Heng Tan, Shan-Hao Jiang, Da-Yuan Zhu   +2 more
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Molecular cloning and characterization of copper amine oxidase from Huperzia serrata

Bioorganic & Medicinal Chemistry Letters, 2012
A cDNA encoding a novel copper amine oxidase (CAO) was cloned and sequenced from the Chinese club moss Huperzia serrata (Huperziaceae), which produces the Lycopodium alkaloid huperzine A. A 2043-bp open reading frame encoded an Mr 76,854 protein with 681 amino acids.
Jieyin, Sun, Hiroyuki, Morita, Guoshen, Chen, Hiroshi, Noguchi, Ikuro, Abe   +4 more
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Indentification of huperzine A-producing endophytic fungi isolated from Huperzia serrata

World Journal of Microbiology and Biotechnology, 2013
This present study was designed to investigate the production of huperzine A (HupA), an acetylcholine inhibitor, which was produced by an endophytic fungi isolated from Huperzia serrata. Screening of 94 endophytic fungal isolates obtained from plant H. serrata was carried out for the production of HupA.
Li-Hui, Dong, San-Wei, Fan, Qing-Zhi, Ling, Bei-Bei, Huang, Zhao-Jun, Wei   +4 more
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Two New Nitrone Alkaloids from Huperzia serrata

Helvetica Chimica Acta, 2008
AbstractTwo new nitrone alkaloids were isolated from the whole plant of Huperzia serrata (Thunb.) Trev. They are both phlegmarine‐type lycopodium alkaloids with a nitrone moiety. Their structures were elucidated on the basis of spectral evidences, and their configurations were established on the basis of optical rotation, CD, and NOESY‐NMR data.
Wen‐Yun Gao, Yi‐Ming Li, Shan‐Hao Jiang, Da‐Yuan Zhu   +3 more
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ChemInform Abstract: A New Lycopodine Alkaloid from Huperzia serrata

ChemInform, 2012
Abstractisolation and structure elucidation of 6α,11α‐dihydroxylycopodine (I)
Wei‐Guang Shan, Feng‐Yun Ren, You‐Min Ying, Cui‐Ping Tong, Zha‐Jun Zhan   +4 more
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Lycopodium alkaloids from Huperzia serrata and their cholinesterase inhibitory activities

Phytochemistry
Huperzia serrata, belonging to the Lycopodiaceae family, has been traditionally utilized for the management of treating rheumatic numbness, arthritic pain, dysmenorrhea, and contusions. This plant is a rich source of lycopodium alkaloids, some of which have demonstrated notable cholinesterase inhibitory activity.
Shuai, Jiang, Bei-Bei, Gao, Yu-Fei, Ou, Qin-Shi, Zhao   +3 more
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Biotransformation of Huperzine B by a Fungal Endophyte of Huperzia serrata

Chemistry & Biodiversity, 2019
AbstractThe biotransformation of huperzine B (hupB), one of the characteristic bioactive constituents of the medicinal plant Huperzia serrata, by a fungal endophyte of the host plant was studied. One new compound, 8α,15α‐epoxyhuperzine B (1), along with two known oxygenated hupB analogs, 16‐hydroxyhuperzine B (2) and carinatumin B (3), was isolated and
Zha‐Jun Zhan, Ting Tian, Yi‐Lian Xu, Hang‐Fei Yu, Cai‐Xue Zhang, Zhi‐Dong Zhang, Qi‐Yong Tang, Wei‐Guang Shan, You‐Min Ying   +8 more
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