Results 111 to 120 of about 4,132 (213)

Achieving and Maintaining Cognitive Vitality With Aging [PDF]

open access: yes, 2001
This report contains the summary results of a workshop held at Canyon Ranch Health Resort in Tucson, Arizona. Physicians and scientists shed light on the process of cognitive aging.
Howard Fillit, Robert N. Butler
core  

High-performance liquid chromatography-mass spectrometry-based acetylcholinesterase assay for the screening of inhibitors in natural medicinal plants [PDF]

open access: yes, 2016
酶是治疗多种疾病的重要靶标,乙酰胆碱酯酶(AChE)的抑制剂是现阶段治疗阿尔兹海默症(AD)最有效的一类药物。从天然产物中寻找适宜患者长期服用、毒副作用小、作用面广等优点的乙酰胆碱酯酶抑制剂(AChEIs)受到了科研工作者的广泛关注。本论文以AChE作为药物靶标,构建基于高效液相色谱-质谱联用技术(HPLC-MS)的在线生物活性检测方法,发展集分离纯化、结构确证和活性筛选于一体的活性导向天然产物研究方法,用来寻找和发现天然药用植物中潜在的AChEIs候选化合物 ...
刘静兰
core  

Neuroprotective Effects of Huperzine A [PDF]

open access: yesNeurosignals, 2005
Rui Wang, Xi Can Tang
openaire   +1 more source

Kaempferol-Phospholipid Complex: Formulation, and Evaluation of Improved Solubility, In Vivo Bioavailability, and Antioxidant Potential of Kaempferol [PDF]

open access: yes, 2016
The current work describes the formulation and evaluation of a phospholipid complex of kaempferol toenhance the latter’s aqueous solubility, in vitro dissolution rate, in vivo antioxidant and hepatoprotectiveactivities, and oral bioavailability.
Anand, Sridhar   +5 more
core   +2 more sources

Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease

open access: yesInternational Journal of Nanomedicine, 2018
Qingqing Meng,1,* Aiping Wang,1,2,* Hongchen Hua,1 Ying Jiang,1 Yiyun Wang,1 Hongjie Mu,1 Zimei Wu,1 Kaoxiang Sun1 1School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong ...
Meng QQ   +7 more
doaj  

Ultrastructural mitochondria changes in perihematomal brain and neuroprotective effects of Huperzine A after acute intracerebral hemorrhage

open access: yesNeuropsychiatric Disease and Treatment, 2015
Haiying Lu,1,* Mei Jiang,2,* Lei Lu,3 Guo Zheng,1 Qiang Dong3 1Department of Neurology, Nanjing Children’s Hospital, Nanjing Medical University, Nanjing, 2Department of Neurology, Shanghai Pudong New Area Gongli Hospital, Shanghai, 3Department of ...
Lu H, Jiang M, Lu L, Zheng G, Dong Q
doaj  

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