Results 111 to 120 of about 12,358,109 (167)

New Monoterpenoid Indole Alkaloids as Potential Neuroprotective Agents from <i>Uncaria hirsuta</i> Haviland. [PDF]

Molecules
Huang XY, Cui J, Wang WL, Zhou HZ, Jiang YC, He X, Chen HL, Li LM.   +7 more
europepmc   +1 more source

Loss of Pathogenicity and Evidence of Horizontal Gene Transfer in Colletotrichum gloeosporioides From a Medicinal Plant. [PDF]

Mol Plant Pathol
Yue X, Yang J, Qi J, Gao S, Huo Q, Guo X, Guo H, Luo J, Wang Y, Zhao Y, Liu R, Wang H, Yi S, Fu Y, Ji X, Wei Y, He W, Guo B.   +17 more
europepmc   +1 more source

Total Syntheses of (−)‐Huperzine Q and (+)‐Lycopladines B and C

Angewandte Chemie, 2014
AbstractUtilizing a late‐stage enamine bromofunctionalization strategy, the twelve‐step total synthesis of (−)‐huperzine Q was accomplished. Furthermore, the first total syntheses of (+)‐lycopladines B and C are described. An unprecedented X‐ray crystal structure of an unusual epoxyamine intermediate is also reported, and the synthetic application of ...
Benke, Hong, Houhua, Li, Jinbao, Wu, Jing, Zhang, Xiaoguang, Lei   +4 more
core   +7 more sources

Australasian Huperzia as potential sources of Huperzine A and B

Planta Medica, 2009
The Lycopodiaceae is an ancient and cosmopolitan family of fern allies that include an estimated 35 Huperzia species occurring throughout the South-East Asian and Australian region. Thirteen species naturally occur in Australia and are found mainly in the tropical rainforests of far north Queensland.
WH Lim, JQG Goodger, AR Field, JAM Holtum, IE Woodrow   +4 more
core   +4 more sources

A cyanopropyl reversed phase chromatography enables resolution of huperzine A and B on analytical and preparative scales

Journal of Separation Science, 2005
AbstractHuperzine A (HupA) and huperzine B (HupB) are two medically important components of Huperzia serrata. It is difficult to obtain high yields of the separation from the plant using conventional liquid extraction and chromatography. However, this study has found that RP chromatography with cyanopropyl (CN) medium was able to separate these two ...
Li, X., Sun, H., Zhang, G., Bi, J., Ma, G., Ma, R., Su, Z.   +6 more
openaire   +4 more sources

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Rapid Purification of Huperzine A and B with Two Polystyrene based Resins by Preparative Low‐Pressure Liquid Chromatography

Journal of Liquid Chromatography and Related Technologies, 2006
A rapid, facile, and environmentally friendly process was developed for purification of huperzine A (HupA) and huperzine B (HupB) from the Chinese traditional herb Huperzia serrata . The process consisted of two steps of preparative low-pressure liquid chromatography (LPLC) on two polystyrene based resins, successively.
Guanghui Ma, Runyu Ma, Zhiguo Su
exaly   +2 more sources

Divergent Total Synthesis of the Lycopodium Alkaloids Huperzine A, Huperzine B, and Huperzine U

The Journal of Organic Chemistry, 2013
Huperzine A, huperzine B, and huperzine U are congeners isolated from the Chinese herb Huperzia serrata (= Lycopodium serratum ) in minuscule amounts. The most efficient total synthesis of huperzine A, the first asymmetric total syntheses of huperzine B, and the first total synthesis of huperzine U have been achieved efficiently in overall yields of 17%
Rui, Ding, Jian-Guo, Fu, Guang-Qiang, Xu, Bing-Feng, Sun, Guo-Qiang, Lin   +4 more
openaire   +2 more sources

Synthesis of a hybrid analog of the acetylcholinesterase inhibitors huperzine A and huperzine B

Tetrahedron Letters, 2001
Abstract The synthesis of a new hybrid analog of the acetylcholinesterase (AChE) inhibitors huperzine A and B is reported. An intramolecular reductive dicarbonyl coupling was used as a key reaction for constructing the tetracyclic ring system.
V Rajendran, Suo-Bao Rong, Ashima Saxena, Bhupendra P Doctor, Alan P Kozikowski   +4 more
openaire   +1 more source

Synthesis and acetylcholinesterase inhibition of derivatives of huperzine B

Bioorganic & Medicinal Chemistry Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Song, Feng, Yu, Xia, Dongmei, Han, Chunyan, Zheng, Xuchang, He, Xican, Tang, Donglu, Bai   +6 more
openaire   +2 more sources