Results 31 to 40 of about 4,296 (130)
A 3-year-old girl with old face appearance: Case report
Journal of Dermatology and Dermatologic Surgery, 2022 Hutchinson–Gilford Progeria Syndrome (HGPS) is a genetic disorder. Patients who suffer from this disorder show premature aging and a “plucked-bird” appearance on the face. This case reports a 3-year-old female, who manifested the symptoms of HGPS.
Hamad A Alfahaad
doaj +1 more source
LivAge: An Online Aging Clock for Murine Transcriptomic Age Estimation
Aging Cell, Volume 25, Issue 9, September 2026.We present LivAge, an online aging clock that estimates murine transcriptomic age from hepatic RNA‐seq data. Externally validated, it detects accelerated aging in progeroid models and quantifies the effect of geroprotective interventions, providing an accurate, accessible, and ready‐to‐use tool for aging research.
Víctor Celemín‐Capaldi +6 more
wiley +1 more source
Hutchinson - Gilford progeria syndrome: A rare case report
Indian Dermatology Online Journal, 2014 Hutchinson - Gilford Progeria Syndrome is a rare genetic disorder characterized by premature aging involving the skin, bones, heart, and blood vessels. We report a three-year-old boy with clinical manifestations characteristic of this syndrome.
Subhash Kashyap +2 more
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Progeria (Hutchinson-Gilford Syndrome): Literature Review and Clinical Case
Вопросы современной педиатрии, 2022 Progeria, or Hutchinson-Gilford Syndrome is a rare disease from the group of laminopathies characterized by premature aging with skin, bones and cardiovascular system lesions.
Natalia V. Buchinskaya +3 more
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Simultaneous Shoulder and Hip Dislocation in a 12-Year-Old Girl with Hutchinson-Gilford Progeria Syndrome [PDF]
Acta Medica Iranica, 2012 Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature ageing disorder that is characterized by accelerated degenerative changes of the cutaneous, musculoskeletal and cardiovascular systems.
Ramin Espandar +2 more
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Mutations Involved in Premature-Ageing Syndromes
The Application of Clinical Genetics, 2021 Fabio CoppedèDepartment of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, ItalyCorrespondence: Fabio CoppedèDepartment of Translational Research and of New Surgical and Medical Technologies ...
Coppedè F
doaj
Pakistan Journal of Pharmaceutical Sciences, 2020 Hutchinson-Gilford progeria syndrome (or Progeria) is an exceptionally rare genetic disorder in children. It is caused by a rare point mutation in the lamin gene. It encodes lamin A protein, resulting in the de-shaping of nuclear membrane.
Bilal Ahmed +5 more
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Akkermansia muciniphila and Its Bioactive Derivatives: Emerging Regulators of Healthy Aging
Aging Cell, Volume 25, Issue 9, September 2026.The beneficial gut bacterium Akkermansia muciniphila (AKK) declines with age but is enriched in healthy centenarians. Supplementation of AKK extends healthspan and alleviates age‐related decline through direct host–microbe interactions and its bioactive derivatives, which collectively enhance gut barrier integrity, restore metabolic homeostasis ...
Ting Zhang +7 more
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Cell & Bioscience, 2022 Background Mesenchymal stem cells (MSCs) are emerging as the mainstay of regenerative medicine because of their ability to differentiate into multiple cell lineages.
Wei Jin +10 more
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Proteostasis of organelles in aging and disease
The FEBS Journal, Volume 293, Issue 18, Page 5600-5626, September 2026.Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
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