Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
Advanced NanoBiomed Research, EarlyView.This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou +4 more
wiley +1 more source
Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4
Journal of Experimental Medicine, 2002 Low molecular weight fragmentation products of the polysaccharide of Hyaluronic acid (sHA) produced during inflammation have been shown to be potent activators of immunocompetent cells such as dendritic cells (DCs) and macrophages.
C. Termeer +9 more
semanticscholar +1 more source
Alveolar accumulation of hyaluronan and alveolar cellular response in bleomycin-induced alveolitis [PDF]
, 1991 O Nettelbladt +4 more
openalex +1 more source
Antibacterial hydrogel: The sniper of chronic wounds
BMEMat, EarlyView.The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian +6 more
wiley +1 more source
Bronchoalveolar lavage fibronectin in patients with sarcoidosis: correlation to hyaluronan and disease activity [PDF]
, 1991 Leif Bjermer +2 more
openalex +1 more source
BMEMat, EarlyView.Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
Novel prognostic markers within the CD44‐stromal ligand network in pancreatic cancer
The Journal of Pathology: Clinical Research, 2019 The dense stroma in pancreatic cancer tumours is rich in secreted extracellular matrix proteins and proteoglycans. Secreted hyaluronan, osteopontin and type IV collagen sustain oncogenic signalling by interactions with CD44s and its variant isoform ...
Oskar Franklin +7 more
doaj +1 more source
Levels of circulating tumor necrosis factor α and interleukin‐6 in patients with rheumatoid arthritis. relationship to serum levels of hyaluronan and antigenic keratan sulfate [PDF]
, 1993 D. Manicourt +5 more
openalex +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
Barrier Immunity, EarlyView.ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia +4 more
wiley +1 more source
BMC Cancer, 2010 Background Hyaluronan accumulation correlates with the degree of malignancy in many solid tumor types, including malignant endometrial carcinomas. To elucidate the mechanism of hyaluronan accumulation, we examined the expression levels of the hyaluronan ...
Kosma Veli-Matti +8 more
doaj +1 more source