Results 141 to 150 of about 114,431 (323)

Accumulation of mechanical forces in tumors is related to hyaluronan content and tissue stiffness

open access: yesPLoS ONE, 2018
Hyaluronan is abundant in the extracellular matrix of many desmoplastic tumors and determines in large part the tumor biochemical and mechanical microenvironment.
C. Voutouri, T. Stylianopoulos
semanticscholar   +1 more source

Expression of Hyaluronan Synthases (HAS1–3) and Hyaluronidases (HYAL1–2) in Serous Ovarian Carcinomas: Inverse Correlation between HYAL1 and Hyaluronan Content

open access: yesBMC Cancer, 2009
Background Hyaluronan, a tumor promoting extracellular matrix polysaccharide, is elevated in malignant epithelial ovarian tumors, and associates with an unfavorable prognosis.
Heikkinen Anna-Mari   +9 more
doaj   +1 more source

Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications

open access: yesRare Metals, EarlyView.
ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin   +4 more
wiley   +1 more source

Stress management in composite biopolymer networks

open access: yes, 2019
Living tissues show an extraordinary adaptiveness to strain, which is crucial for their proper biological functioning. The physical origin of this mechanical behaviour has been widely investigated using reconstituted networks of collagen fibres, the ...
Burla, Federica   +4 more
core   +2 more sources

Regulation of Hyaluronan Synthesis in Vascular Diseases and Diabetes [PDF]

open access: gold, 2015
Paola Moretto   +7 more
openalex   +1 more source

Selective Membrane Protein Enrichment Enables Defined Biomimetic Nanoparticles for Endothelial Targeting

open access: yesSmall, EarlyView.
Particular nanoparticles (PNPs), engineered with defined enrichment of leukocyte adhesion membrane proteins, demonstrate superior targeting of inflamed sites in a microfluidic inflamed vessel model under flow conditions. This selective membrane protein enrichment enhances targeting efficiency while improving nanoparticle production reproducibility and ...
Sivan Arber Raviv   +4 more
wiley   +1 more source

Rapid Generation of Fusable Cell Beads for Multi‐Scale Human Living Materials Assembly

open access: yesSmall Methods, EarlyView.
Living beads are produced through the combination of metabolic glycoengineering, click chemistry, and superhydrophobic surfaces, to develop a spheroid alternative for bottom‐up tissue engineering and disease modeling. The living beads present a size independent of cell density and a rapid fabrication methodology, providing a platform that can fuse into
Beatriz S. Moura   +5 more
wiley   +1 more source

Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression

open access: yesCase Reports in Obstetrics and Gynecology, 2018
Intravenous leiomyomatosis (IVL) is a rare benign neoplasm. Herein, we describe two cases of IVL at different levels of progression. The tumor in Case 1 was extensive, invading the right atrium after a hysterectomy for a uterine myoma.
Haruhisa Konishi   +8 more
doaj   +1 more source

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