Results 21 to 30 of about 58,192 (295)

Marine Biomaterials: Hyaluronan

open access: yesMarine Drugs, 2023
The marine-derived hyaluronic acid and other natural biopolymers offer exciting possibilities in the field of biomaterials, providing sustainable and biocompatible alternatives to synthetic materials. Their unique properties and abundance in marine sources make them valuable resources for various biomedical and industrial applications.
Rasha. M. Abdel-Rahman   +1 more
openaire   +3 more sources

MCF10CA Breast Cancer Cells Utilize Hyaluronan-Coated EV-Rich Trails for Coordinated Migration

open access: yesFrontiers in Oncology, 2022
Invasion of tumor cells through the stroma is coordinated in response to migratory cues provided by the extracellular environment. One of the most abundant molecules in the tumor microenvironment is hyaluronan, a glycosaminoglycan known to promote many ...
Niina Aaltonen   +7 more
doaj   +1 more source

Hyaluronan-Based Gel Promotes Human Dental Pulp Stem Cells Bone Differentiation by Activating YAP/TAZ Pathway

open access: yesCells, 2021
Background: Hyaluronans exist in different forms, accordingly with molecular weight and degree of crosslinking. Here, we tested the capability to induce osteogenic differentiation in hDPSCs (human dental pulp stem cells) of three hyaluronans forms ...
Marcella La Noce   +11 more
semanticscholar   +1 more source

Diagnostic usefulness of Hyaluronan and Hyaluronan Synthases-A Review [PDF]

open access: yesInternational Journal of Multidisciplinary and Current Research, 2018
The first isolation of HA was in the year 1934, but research on HA and its clinical significance in health and disease started only in the year 1970. Both HA and HASs play a significant role in many physiological and pathological processes. The cellular HA synthesis are coordinated collectively by HASs.
Dr.Oviya Senthilraj   +3 more
openaire   +3 more sources

The where, when, how and why of hyaluronan binding by immune cells

open access: yesFrontiers in Immunology, 2015
Hyaluronan is made and extruded from cells to form a pericellular or extracellular matrix (ECM) and is present in virtually all tissues in the body. The size and form of hyaluronan present in tissues is indicative of a healthy or inflamed tissue, and the
Sally S. M. Lee-Sayer   +5 more
doaj   +1 more source

Hyaluronan and cardiac regeneration [PDF]

open access: yesJournal of Biomedical Science, 2014
Hyaluronan (HA) is abundantly expressed in several human tissues and a variety of roles for HA has been highlighted. Particularly relevant for tissue repair, HA is actively produced during tissue injury, as widely evidenced in wound healing investigations.
BONAFÈ, FRANCESCA   +5 more
openaire   +3 more sources

Mycobacteria exploit host hyaluronan for efficient extracellular replication. [PDF]

open access: yesPLoS Pathogens, 2009
In spite of the importance of hyaluronan in host protection against infectious organisms in the alveolar spaces, its role in mycobacterial infection is unknown.
Yukio Hirayama   +11 more
doaj   +1 more source

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

open access: yesNature Communications, 2020
In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains unknown.
F. Soria   +11 more
semanticscholar   +1 more source

Hyaluronan in skin [PDF]

open access: yesJournal of Internal Medicine, 1997
Juhlin L (University Hospital, Uppsala, Sweden). Hyaluronan in skin (Minisymposium: Hyaluronan) J Intern Med 1997; 242: 61–6.Because of the abundance of hyaluronan in skin, interest was early focused on variation in the content of the polysaccharide in various pathological conditions of this tissue.
openaire   +3 more sources

Importance of hyaluronan biosynthesis and degradation in cell differentiation and tumor formation

open access: yesBrazilian Journal of Medical and Biological Research, 2003
Hyaluronan is an important connective tissue glycosaminoglycan. Elevated hyaluronan biosynthesis is a common feature during tissue remodeling under both physiological and pathological conditions.
P. Heldin
doaj   +1 more source

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