Results 31 to 40 of about 114,431 (323)

Hyaluronan and Hyaluronidase, which is better for embryo development? [PDF]

, 2016
Our aim was to examine size-specific effects of Hyaluronan (HA) on preimplantation embryo development. We investigated the effects of Hyalovet (HA, 500–750 kDa; the size produced by HA synthase-3, which is abundant in the oviduct), or HA treated with ...
Ali A. Fouladi-Nashta, Aruffo, Aviles, Bastow, Bergqvist, Block, Bourguignon, Choudhary, Csoka, Dicker, Fenwick, Fouladi-Nashta, Furnus, Furnus, Georgiou, Hahnel, Hess, Kabir A. Raheem, Lane, Laurent, Lesley, Lloyd, Marei, Marei, Mariani, Matwee, Mazdak Salavati, Mehta, Mohey-Elsaeed, Muhammad Khalid, Neira, Oesterreicher, Ohno-Nakahara, Pandey, Pushpakumara, Raheem, Robinson, Rozen, Russell, Ryan, Saliba, Schmidt, Seytanoglu, Stern, Stevenson, Tienthai, Tina Tremaine, Tombolan, Toole, Torner, Ulbrich, Waleed F.A. Marei, Wang, Wathes, Watson, Way, Weigel, Xu, Yevdokimova, Yoon   +59 more
core   +2 more sources

Importance of hyaluronan biosynthesis and degradation in cell differentiation and tumor formation

Brazilian Journal of Medical and Biological Research, 2003
Hyaluronan is an important connective tissue glycosaminoglycan. Elevated hyaluronan biosynthesis is a common feature during tissue remodeling under both physiological and pathological conditions.
P. Heldin
doaj   +1 more source

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. [PDF]

, 2019
IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe ...
Byanyima, Patrick, Chang, Emily G, Crothers, Kristina, Davis, J Lucian, Huang, Laurence, Hunt, Peter W, Kaswabuli, Sylvia, Lalitha, Rejani, Lederman, Michael M, Lin, Jue, Moisi, Daniela, Moore, Julia, Musisi, Emmanuel, Sanyu, Ingvar, Sessolo, Abdulwahab, Wang, Richard J, Worodria, William   +16 more
core   +2 more sources

Hyaluronic acid (hyaluronan): a review

, 2018
Hyaluronic acid (HA) is a high molecular weight biopolysacharide, discovered in 1934, by Karl Meyer and his assistant, John Palmer in the vitreous of bovine eyes.
J. Nečas, L. Bartošíková, P. Brauner, J. Kolar   +3 more
semanticscholar   +1 more source

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

Nature Communications, 2020
In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains unknown.
F. Soria, C. Paviolo, E. Doudnikoff, Marie-Laure Arotcarena, Antony Lee, N. Danné, A. Mandal, P. Gosset, B. Dehay, L. Groc, L. Cognet, E. Bézard   +11 more
semanticscholar   +1 more source

Hyaluronic acid: perspectives in upper aero-digestive tract. A systematic review [PDF]

, 2015
Background: To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper aerodigestive tract (UADT).
Baptista, Peter, Casale, Manuele, Moffa, Antonio, Oliveto, Giuseppe, Pace, Annalisa, Sabatino, Lorenzo, Salvinelli, Fabrizio, Vitali, Massimiliano   +7 more
core   +3 more sources

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Hyaluronan-Based Gel Promotes Human Dental Pulp Stem Cells Bone Differentiation by Activating YAP/TAZ Pathway

Cells, 2021
Background: Hyaluronans exist in different forms, accordingly with molecular weight and degree of crosslinking. Here, we tested the capability to induce osteogenic differentiation in hDPSCs (human dental pulp stem cells) of three hyaluronans forms ...
Marcella La Noce, A. Stellavato, V. Vassallo, M. Cammarota, L. Laino, V. Desiderio, Vitale Del Vecchio, G. F. Nicoletti, V. Tirino, G. Papaccio, C. Schiraldi, G. Ferraro   +11 more
semanticscholar   +1 more source

One-electron oxidation and reduction of glycosaminoglycan chloramides: a kinetic study. [PDF]

, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, these being significant components of the extracellular matrix (ECM).
A.W.J. Paterson, Akeel, Al-Assaf, Al-Assaf, B.J. Parsons, Balazs, C. Houee-Levin, Camenisch, Chawla, D.J. Heyes, Dogliotti, Eriksen, Hardingham, Hawkins, Hayon, Hayon, Heckel, Heinecke, Huie, Ivanov, J.-L. Marignier, Jiang, Johnson, Kennett, Kennett, Kettle, Laurent, Laurent, McElroy, McElroy, McGowan, Milner, Misra, Parsons, Parsons, Pattison, Pattison, Pattison, Pe Myint, Poskrebyshev, Redpath, Rees, Rees, Rees, Rees, Rees, Rees, S. Sibanda, Schwarz, Stern, Swallow, Tang, Thomas, Thomas, Thorne, Toole, Toole, Toole, Turley, van Golen, von Sonntag, Weeks, Weiss, Weiss, Wine, Wolfenden, Woods, Zao   +67 more
core   +1 more source

The Influence of Hofmeister Series Ions on Hyaluronan Swelling and Viscosity

Molecules, 2008
The dissolution of hyaluronan in water leads to its degradation, and as a resultits molecular weight decreases. The degradation of hyaluronan is mainly influenced bytemperature, solution composition, and also its pH.
Vladimír Velebný, Alena Pokopcová, Lenka Gřundělová, Marián Lehocký, Júlia Varhaníková, AleÅ¡ Mráček   +5 more
doaj   +1 more source