Results 111 to 120 of about 28,152 (259)
Clinical &Experimental Allergy, EarlyView.Carrageenans, widely used food additives, disrupted intestinal epithelial integrity in a gut‐on‐a‐chip model. All types (κ‐, ɩ‐, λ‐) induced cytotoxicity, inflammation and tight junction (TJ) disruption, triggering TNF‐mediated immune responses. λ‐Carrageenan had the most severe effects, supporting the Epithelial Barrier Theory linking food additives ...
Na Sun +13 more
wiley +1 more source
Metabolism and mechanisms of action of hyaluronan in human biology
, 2018 Hyaluronan is a ubiquitous high-molecular weight polymer of repeated disaccharides of glucuronic acid andN-acetylglucosamine. It is a membrane-bound, viscous material extruded into the extracellular matrix after being synthesized in the cytoplasm by ...
Narendranath Vikkath +2 more
core +1 more source
Involvement of Hyaluronan and Its Receptor CD44 with Choroidal Neovascularization
Investigative Opthalmology & Visual Science, 2009 CD44 is a cell-surface adhesion molecule and receptor for hyaluronan (HA), one of the major extracellular matrix components. The purpose of the present study was to clarify a role of HA and CD44 in the development of choroidal neovascularization (CNV).Laser photocoagulation was used to induce CNV in C57BL/6 mice or CD44-deficient mice.
Hiroshi, Mochimaru +14 more
openaire +2 more sources
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The FEBS Journal, EarlyView.The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Biology Open, 2016 Receptor clustering is known to trigger signalling events that contribute to critical changes in cellular functions. Faithful imaging of such clusters by means of fluorescence microscopy relies on the application of adequate cell fixation methods prior ...
Tess A. Stanly +6 more
doaj +1 more source
Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
The FEBS Journal, EarlyView.Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
wiley +1 more source
Receptors of cell adhesion and cellular recognition /
, 1996 Volume 3 of Biomembranes covers receptors of cell adhesion and cellular recognition. Proteins in the plasma membrane of cells are heavily involved in processes of cell adhesion, but such proteins were not actually isolated and characterized until the mid-
Lee, A. G.
core
Sperm Separation and Selection Techniques to Mitigate Sperm DNA Damage
LifeSemen preparation and sperm selection techniques exploit the morphological and physiological characteristics of sperm function, including motility, morphology, density, and maturity, as reflected by their cell-surface charge and the expression of ...
Steven Fleming +2 more
doaj +1 more source
Biomolecules, 2019 Hyaluronic acid (hyaluronan, HA) is a critical component of the extracellular matrix and plays an important biological function of interacting with different molecules and receptors.
Wenwei Han +5 more
doaj +1 more source
An update on the landscape of collagen bioactive fragments
The FEBS Journal, EarlyView.The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source