Results 101 to 110 of about 28,152 (259)

Cytokines, growth factors and macromolecules as mediators of implantation in mammalian species

International Journal of Veterinary Science and Medicine, 2018
Implantation is one of the most critical steps in mammalian reproduction and implantation failure constitutes a major cause of infertility in both animals and humans.
Kabir A. Raheem
doaj   +1 more source

Ginsenoside Rg1 Ameliorates LPS‐Induced Sepsis‐Associated Lung Injury in Mice via VEGFC/D‐VEGFR3 Signaling‐Mediated Lymphangiogenesis and Lymphatic Remodeling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang, Lan Hu, Chun‐Pan Zhang, Wen‐Jie Qi, Yu‐Guo Song   +4 more
wiley   +1 more source

Receptor for Hyaluronan Mediated Motility (RHAMM)/Hyaluronan Axis in Breast Cancer Chemoresistance

Cancers
Background/Objectives: Receptor for hyaluronan-mediated motility (RHAMM) is a hyaluronan (HA) receptor, which exerts diverse biological functions in not only physiological but also pathological conditions in human malignancies, including breast cancer.
Shiori Fujisawa, Kiyoshi Takagi, Mio Yamaguchi-Tanaka, Ai Sato, Yasuhiro Miki, Minoru Miyashita, Hiroshi Tada, Takanori Ishida, Takashi Suzuki   +8 more
openaire   +2 more sources

Diagnostic Value of Glycocalyx Shedding in Blood for Differentiating between Parkinson's Disease and Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Blood–brain barrier disruption is increasingly recognized in synucleinopathies, but the role of the endothelial glycocalyx (GLX) in Parkinson's disease (PD) and multiple system atrophy (MSA) remains unclear. Objectives The aim was to determine whether plasma GLX markers differ between PD, MSA, and healthy controls (HC), relate to ...
Jonas Folke, Brian DellaValle, Mathias Lindh Jørgensen, Phillip Bredahl Mogensen, Casper Hempel, Jørgen Rungby, Anne‐Mette Hejl, Annemette Løkkegaard, Lisette Salvesen, Sara Bech, Mette Møller, Erik Hvid Danielsen, Morten Blaabjerg, Matthias Bode, Tomasz Brudek, Susana Aznar   +15 more
wiley   +1 more source

Engineering a Tissue Mimic for Predictive Nanoparticle Assessment

, 2015
Bio-scientific research has relied heavily on models of cell monolayers cultured on plastic. For most cell types, this does not represent their in vivo tissue organisation well. As a result they behave differently in vitro from in vivo, leading to poorly
Tan, NS
core  

Hyaluronan oligosacharides and their biological function [PDF]

, 2010
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biophysic and Physical Chemistry Candidate: Bc. Barbora Kučerová Supervisor: Doc. Ing. Alice Lázníčková, CSc.
Kučerová, Barbora
core  

Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension

Frontiers in Physiology, 2018
Background: Pulmonary hypertension (PH) is a devastating and progressive disease characterized by excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) and remodeling of the lung vasculature.
Tinne C. J. Mertens, Ankit Hanmandlu, Ly Tu, Ly Tu, Carole Phan, Carole Phan, Scott D. Collum, Ning-Yuan Chen, Tingting Weng, Jonathan Davies, Chen Liu, Holger K. Eltzschig, Soma S. K. Jyothula, Keshava Rajagopal, Yang Xia, Ashrith Guha, Brian A. Bruckner, Michael R. Blackburn, Christophe Guignabert, Christophe Guignabert, Harry Karmouty-Quintana   +20 more
doaj   +1 more source

Detection of the Hyaluronan Receptor CD44 in the Bovine Oviductal Epithelium

Journal of Reproduction and Development, 2005
Hyaluronan is involved in fundamental reproductive events such as sperm storage in the female reproductive tract, fertilization, and early embryo development, these functions are presumably mediated by its major cell surface receptor, CD44. The present study was conducted to investigate the presence and localization of CD44 in the bovine oviductal ...
BERGQVIST, Ann-Sofi, YOKOO, Masaki, BÅGE, Renée, SATO, Eimei, RODRÍGUEZ-MARTÍNEZ, Heriberto   +4 more
openaire   +3 more sources

Hyaluronan cross-linking: A protective mechanism in inflammation?

, 2005
Production of the glycosaminoglycan hyaluronan is increased at sites of inflammation, often correlating with the accumulation of leukocytes. Mounting evidence suggests that this polysaccharide can be organized into a wide variety of molecular ...
Day, Anthony J.; id_orcid, De La Motte, Carol A.   +1 more
core   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source