Results 81 to 90 of about 28,152 (259)

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

Fluid bolus increases plasma hyaluronan concentration compared to follow-up strategy without a bolus in oliguric intensive care unit patients

Scientific Reports
Fluid therapy is a fundamental part of supportive therapy in critical care. However, it is also a suspected risk for endothelial glycocalyx degradation which is associated with poor clinical outcomes.
Maija Serlo, Nina Inkinen, Päivi Lakkisto, Miia Valkonen, Anni Pulkkinen, Tuomas Selander, Ville Pettilä, Suvi T. Vaara   +7 more
doaj   +1 more source

Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery

International Journal of Cell Biology, 2015
The outcome of patients with cancer has improved significantly in the past decade with the incorporation of drugs targeting cell surface adhesive receptors, receptor tyrosine kinases, and modulation of several molecules of extracellular matrices (ECMs ...
Suniti Misra, Vincent C. Hascall, Ilia Atanelishvili, Ricardo Moreno Rodriguez, Roger R. Markwald, Shibnath Ghatak   +5 more
doaj   +1 more source

Divergent temporal expression of hyaluronan metabolizing enzymes and receptors with craniotomy vs. controlled cortical impact injury in rat brain: A pilot study

Frontiers in Neurology, 2014
Traumatic brain injury triggers many secondary changes in tissue biology which ultimately determine the extent of injury and clinical outcome. Hyaluronan (hyaluronic acid, HA) is a protective cementing gel present in the intercellular spaces whose ...
Guoqiang eXing, Ming eRen, Ajay eVerma
doaj   +1 more source

The Hyaluronan Receptor RHAMM Regulates Extracellular-regulated Kinase [PDF]

Journal of Biological Chemistry, 1998
We have identified two RHAMM (receptor for hyaluronan-mediated motility) isoforms that encode an alternatively spliced exon 4 (Hall, C. L., Yang, B., Yang, X., Zhang, S., Turley, M., Samuel, S., Lange, L. A., Wang, C., Curpen, G. D., Savani, R. C., Greenberg, A. H., and Turley, E. A.
Zhang, S., Chang, M. C., Zylka, D., Turley, S., Harrison, R., Turley, E. A.   +5 more
openaire   +2 more sources

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

Importance of hyaluronan-CD44 interactions in inflammation and tumorigenesis.

, 2008
Hyaluronan is an apparently simple polysaccharide that is responsible for tissue hydration but also stimulates cell proliferation, migration, and differentiation via binding to cell surface receptors, such as CD44.
Skandalis, Spyros S.,, NISHITSUKA K, SKANDALIS SS, PORSCH H, Porsch, Helena,, Nishitsuka, Koichi,, HELDIN P, Heldin, Paraskevi,, KAROUSOU, EVGENIA, Karousou, Eugenia,, BERNERT B, Bernert, Berit,   +11 more
core   +1 more source

The myofascial rheostat: hyaluronan molecular weight dynamics and purinergic signalling as a physiological feedback system

Frontiers in Physiology
Fascia, the connective tissue network enveloping muscles, organs, and viscera, functions as a hyaluronan (HA)-rich adaptive interface that senses and responds to inflammatory cues. This narrative review synthesizes ECM literature across niches to examine
Karen B. Kirkness, Fabiana C. da Silva, Fabiana C. da Silva, Robert Schleip, Robert Schleip, Robert Schleip, Ronaldo H. Cruvinel-Júnior, Suzanne Scarlata   +7 more
doaj   +1 more source

Hyaluronic Acid (HA) Receptors and the Motility of Schwann Cell(-Like) Phenotypes

Cells, 2020
The cluster of differentiation 44 (CD44) and the hyaluronan-mediated motility receptor (RHAMM), also known as CD168, are perhaps the most studied receptors for hyaluronic acid (HA); among their various functions, both are known to play a role in the ...
Sihem Ouasti, Alessandro Faroni, Paul J. Kingham, Matilde Ghibaudi, Adam J. Reid, Nicola Tirelli   +5 more
doaj   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source