Results 131 to 140 of about 2,309,824 (325)

Cholangiocytes: Cell transplantation [PDF]

, 2017
Background:Due to significant limitations to the access to orthotropic liver transplantation, cell therapies forliver diseases have gained large interest worldwide.Scope of review:To revise current literature dealing with cell therapy for liver diseases.
Alvaro, Domenico, Bragazzi, MARIA CONSIGLIA, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Ridola, Lorenzo   +5 more
core   +1 more source

Critical importance of appropriate fixation conditions for faithful imaging of receptor microclusters

Biology Open, 2016
Receptor clustering is known to trigger signalling events that contribute to critical changes in cellular functions. Faithful imaging of such clusters by means of fluorescence microscopy relies on the application of adequate cell fixation methods prior ...
Tess A. Stanly, Marco Fritzsche, Suneale Banerji, Esther García, Jorge Bernardino de la Serna, David G. Jackson, Christian Eggeling   +6 more
doaj   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Synthesis of heparosan oligosaccharides by Pasteurella multocida PmHS2 single-action transferases [PDF]

, 2012
Pasteurella multocida heparosan synthase PmHS2 is a dual action glycosyltransferase that catalyzes the polymerization of heparosan polymers in a non-processive manner.
Boeriu, C.G., Broek, L.A.M., van den, Chavaroche, A.A.E., Eggink, G.   +3 more
core   +2 more sources

Preparation, Characterization, and Inhibition of Hyaluronic Acid Oligosaccharides in Triple-Negative Breast Cancer

Biomolecules, 2019
Hyaluronic acid (hyaluronan, HA) is a critical component of the extracellular matrix and plays an important biological function of interacting with different molecules and receptors.
Wenwei Han, Lili Song, Yingdi Wang, Youjing Lv, Xiangyan Chen, Xia Zhao   +5 more
doaj   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Thymosin α1 Interacts with Hyaluronic Acid Electrostatically by Its Terminal Sequence LKEKK [PDF]

, 2017
Thymosin α1 (Tα1), is a peptidic hormone, whose immune regulatory properties have been demonstrated both in vitro and in vivo and approved in different countries for treatment of several viral infections and cancers.
Billich, Bourguignon, Enrico Garaci, Francesca Pica, Kullavanuaya, Low, Low, Malinda, Maurizio Paci, Nepravishta, Paola Sinibaldi Vallebona, Pilarski, Ridvan Nepravishta, Tuthill, Walter Mandaliti, Wüthrich, Xu, Yang, Yang   +18 more
core   +2 more sources

Comparative Studies on the Structure and Biological Activities of Two New Polysaccharides From Tricholoma flavovirens (TF‐P) and Trametes versicolor (TV‐P)

Food Frontiers, EarlyView.
Two water‐soluble polysaccharides were isolated and purified from Tricholoma flavovirens (TF‐P) and Trametes versicolor (TV‐P), respectively. The structures of the two polysaccharides were identified by combining GPC, FT‐IR, HPLC, GC–MS, and NMR, and the structure–activity relationship has also been studied using immune cells and tumor cells. TV‐P with
Zheng‐Ao Sun, Nihui Zhao, Langlin Zheng, Feng Pan, Xiang Ding, Yiling Hou   +5 more
wiley   +1 more source

Receptor for Hyaluronan Mediated Motility (RHAMM)/Hyaluronan Axis in Breast Cancer Chemoresistance

Cancers
Background/Objectives: Receptor for hyaluronan-mediated motility (RHAMM) is a hyaluronan (HA) receptor, which exerts diverse biological functions in not only physiological but also pathological conditions in human malignancies, including breast cancer.
Shiori Fujisawa, Kiyoshi Takagi, Mio Yamaguchi-Tanaka, Ai Sato, Yasuhiro Miki, Minoru Miyashita, Hiroshi Tada, Takanori Ishida, Takashi Suzuki   +8 more
openaire   +2 more sources

Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity. [PDF]

, 1994
Christine Hall, Chao Wang, Laurie Lange, EA Turley   +3 more
openalex   +1 more source