Results 21 to 30 of about 2,309,824 (325)
Signaling Properties of Hyaluronan Receptors* [PDF]
Journal of Biological Chemistry, 2002 E. Turley, P. Noble, L. Bourguignon
semanticscholar +4 more sources
Immunological functions of hyaluronan and its receptors in the lymphatics
Immunological Reviews, 2009 Summary: The lymphatic system is best known for draining interstitial fluid from the tissues and returning it to the blood circulation. However, the lymphatic system also provides the means for immune surveillance in the immune system, acting as conduits that convey soluble antigens and antigen‐presenting cells from the tissues to the lymph nodes ...
D. Jackson
semanticscholar +3 more sources
Impacts of Hyaluronan on Extracellular Vesicle Production and Signaling [PDF]
CellsHyaluronan (HA) is a critical component of cell and tissue matrices and an important signaling molecule. The enzymes that synthesize and process HA, as well as the HA receptors through which the signaling properties of HA are transmitted, have been ...
Melanie A. Simpson
doaj +2 more sources
Fluid bolus increases plasma hyaluronan concentration compared to follow-up strategy without a bolus in oliguric intensive care unit patients [PDF]
Scientific ReportsFluid therapy is a fundamental part of supportive therapy in critical care. However, it is also a suspected risk for endothelial glycocalyx degradation which is associated with poor clinical outcomes.
Maija Serlo +7 more
doaj +2 more sources
The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan. [PDF]
The Journal of cell biology, 1992 The hyaluronan receptor belongs to the polymorphic family of CD44 glycoproteins, which have been implicated in a variety of cellular functions including adhesion to hyaluronan and collagen, the binding of lymphocytes to high endothelial cells during extravasation, and conferring metastatic potential to carcinoma cells.
Charles B. Underhill +2 more
openaire +3 more sources
The Hyaluronan/CD44 Axis: A Double-Edged Sword in Cancer
International Journal of Molecular Sciences, 2023 Hyaluronic acid (HA) receptor CD44 is widely used for identifying cancer stem cells and its activation promotes stemness. Recent evidence shows that overexpression of CD44 is associated with poor prognosis in most human cancers and mediates therapy ...
Nicola Cirillo
semanticscholar +1 more source
Localization of CD44 (Hyaluronan Receptor) and Hyaluronan in Rat Mandibular Condyle [PDF]
Journal of Histochemistry & Cytochemistry, 2005 CD44 is a multifunctional adhesion molecule that binds to hyaluronan (HA), type I collagen, and fibronectin. We investigated localization of CD44 and HA in mandibular condylar cartilage compared with the growth plate and the articular cartilage, to clarify the characteristics of chondrocytes.
Hiroaki Nakamura +4 more
openaire +3 more sources
Knock-down of CD44 regulates endothelial cell differentiation via NFκB-mediated chemokine production. [PDF]
PLoS ONE, 2014 A striking feature of microvascular endothelial cells is their capacity to fuse and differentiate into tubular structures when grown in three-dimensional (3D) extracellular matrices, in collagen or Matrigel, mimicking the in vivo blood vessel formation ...
Berit Olofsson +2 more
doaj +1 more source
Cell Adhesion & Migration, 2023 The sensitivity to cold plasma is specific to tumor cells while leaving normal tissue cells unaffected. This is the desired challenge in cancer therapy. Therefore, the focus of this work was a comparative study concerning the plasma sensitivity of dermal
Anna-Christin Golz +5 more
doaj +1 more source