Results 31 to 40 of about 27,596 (198)
Hyaluronan goes to great length
Cell Stress, 2020 Hyaluronan is a major non-protein component of extracellular matrix that affects biomechanical properties of tissues and interacts with cell receptors.
Vera Gorbunova +2 more
doaj +1 more source
mBio, 2023 Bacterial infections remain a significant cause of adverse pregnancy outcomes. Ascending infection of group B streptococcus (GBS) or Streptococcus agalactiae from the lower genital tract to the amniotic cavity leads to fetal injury, preterm births, or ...
Michelle Coleman +13 more
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Versican—A Critical Extracellular Matrix Regulator of Immunity and Inflammation
Frontiers in Immunology, 2020 The extracellular matrix (ECM) proteoglycan, versican increases along with other ECM versican binding molecules such as hyaluronan, tumor necrosis factor stimulated gene-6 (TSG-6), and inter alpha trypsin inhibitor (IαI) during inflammation in a number ...
Thomas N. Wight +7 more
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Ligand Binding and Signaling of HARE/Stabilin-2
Biomolecules, 2019 The Stabilin receptors are a two-member family in the type H class of scavenger receptors. These dynamic receptors bind and internalize multiple ligands from the cell surface for the purpose of clearing extracellular material including some synthetic ...
Edward N. Harris, Fatima Cabral
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Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Biomolecules, 2019 Since the discovery of a novel liver hyaluronan (HA) clearance receptor in 1981 by Laurent, Fraser and coworkers, 22 different ligands cleared by the renamed receptor (the Hyaluronan Receptor for Endocytosis (HARE); Stabilin-2 (Stab2)) were discovered ...
Paul H. Weigel
doaj +1 more source
Современная ревматология, 2013 The paper presents data on osteoarthrosis treatment using hyaluronic acid (HA) preparations, on the functions of hyaluronan (HN) in synovial fluid (SF), synovial tissue, and articular cartilage, and on differences in the symptom-modifying effect of HN ...
Natalia Vladimirovna Chichasova
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Integrated approaches for the recognition of small molecule inhibitors for Toll-like receptor 4
Computational and Structural Biotechnology Journal, 2023 Toll-like receptors (TLRs) are pattern recognition receptors present on the surface of cells playing a crucial role in innate immunity. One of the TLRs, TLR4, recognizes LPS (Lipopolysaccharide) as its ligand leading to the release of anti-inflammatory ...
Shailya Verma +2 more
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Hyaluronan receptors involved in cytokine induction in monocytes [PDF]
Glycobiology, 2008 During inflammation, lower molecular weight fragments of hyaluronan accumulate, and this is known to be inflammatory and immune-stimulatory. In diseases such as inflammatory bowel disease, inflammatory cells bind to hyaluronan; however, the cellular response and molecular mechanism of hyaluronan-hyaluronan receptor interactions in mononuclear cells are
Hitoshi, Yamawaki +9 more
openaire +2 more sources
Advanced Materials, EarlyView.Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source