Results 51 to 60 of about 28,152 (259)

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges

, 2000
Jarchow J, Fritz J, Anselmetti D, et al. Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges. Journal of structural biology.
Fritz, Jürgen, Gerosa, Daniela, Burger, Max M., Calabro, Anthony, Fernandez-Busquets, Xavier, Hascall, Vincent C., Jarchow, Janina, Anselmetti, Dario ; https://orcid.org/   +7 more
core   +1 more source

Hyaluronidase-induced matrix remodeling contributes to long-term synaptic changes

Frontiers in Neural Circuits
Extracellular brain space contains water, dissolved ions, and multiple other signaling molecules. The neural extracellular matrix (ECM) is also a significant component of the extracellular space.
Rostislav Sokolov, Rostislav Sokolov, Viktoriya Krut', Viktoriya Krut', Vsevolod Belousov, Vsevolod Belousov, Vsevolod Belousov, Vsevolod Belousov, Andrey Rozov, Andrey Rozov, Irina V. Mukhina, Irina V. Mukhina   +11 more
doaj   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source

One-electron oxidation and reduction of glycosaminoglycan chloramides: a kinetic study.

, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, these being significant components of the extracellular matrix (ECM).
Parsons, BJ, Houee-Levin, C., Sibanda, S., Heyes, D. J.; id_orcid, Marignier, JL, Sibanda, S, Parsons, B. J., Marignier, J. L., Paterson, A. W J, Houee-Levin, C, Paterson, AW, Heyes, DJ   +11 more
core   +1 more source

Identification of two hyaluronan-binding domains in the hyaluronan receptor RHAMM.

Journal of Biological Chemistry, 1993
We have identified two discrete hyaluronan- (HA) binding domains in the HA receptor RHAMM (Receptor for HA-Mediated Motility) that mediates the locomotion of H-ras transformed fibroblasts. A complete RHAMM cDNA (1.43 kilobases (kb)) was expressed as a fusion protein with pGEX-2T in Escherichia coli HB101 and was shown to bind specifically to both ...
B, Yang, L, Zhang, E A, Turley
openaire   +2 more sources

Localization of hyaluronan and the hyaluronan receptor ICAM-1 in rheumatoid synovia—a histochemical study [PDF]

Acta Orthopaedica Scandinavica, 1995
The major site for elimination of HA from the bloodstream is via receptor mediated endocytosis by liver endothelial cells (LEC) (Fraser and Laurent 1989, Laurent and Fraser 1992). The HA receptor (HAR) on LEC has been characterized and isolated from rat LEC membranes (Forsberg and Gustafson 1991).
Stefan Gustafson, Anna Engström-Laurent, Tarja Wikström, Ann-Marie Gustafson   +3 more
openaire   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics

Nature Communications
Immune surveillance involves the continual migration of antigen-scavenging immune cells from the tissues to downstream lymph nodes via lymphatic vessels.
Fouzia Bano, Suneale Banerji, Tao Ni, Dixy E. Green, Kalila R. Cook, Iain W. Manfield, Paul L. DeAngelis, Emanuele Paci, Martin Lepšík, Robert J. C. Gilbert, Ralf P. Richter, David G. Jackson   +11 more
doaj   +1 more source

Hyaluronan in the lymphatics: The key role of the hyaluronan receptor LYVE-1 in leucocyte trafficking [PDF]

Matrix Biology, 2019
LYVE-1, a close relative of the leucocyte receptor, CD44, is the main receptor for hyaluronan (HA) in lymphatic vessel endothelium and a widely used marker for distinguishing between blood and lymphatic vessels. Enigmatic for many years because of its anomalous HA-binding characteristics, the function of LYVE-1 has just recently been identified as that
openaire   +3 more sources