Results 41 to 50 of about 19,597 (211)

Effect of red ginseng NaturalGEL on skin aging

Journal of Ginseng Research, 2020
Background: In aged skin, degradation of collagen fibers, which occupy the majority of the extracellular matrix in the dermis, and changes of aquaporin 3 (AQP3) and skin constituents, such as hyaluronic acid and ceramide, cause wrinkles and decrease skin
Ye Hyang Kim, Hye Rim Park, So Yoon Cha, So Hun Lee, Jung Wung Jo, Jung Nam Go, Kang Hyuk Lee, Su Yeon Lee, Song Seok Shin   +8 more
doaj   +1 more source

ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis [PDF]

, 2017
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, and several molecular pathways that underlie the molecular tumorigenesis of HNSCC have been identified. Among them, amplification or overexpression of ΔNp63 isoforms
Anemone, Lucia, Bongiorno-Borbone, Lucilla, Compagnone, Mirco, Fierro, Claudia, Gatti, Veronica, Markert, Elke Katrin, Mauriello, Alessandro, Melino, Gerry, Peschiaroli, Angelo, Presutti, Dario, Ruberti, Giovina, Vousden, Karen H, Zhou, Huiqing   +12 more
core   +2 more sources

The Calcium-Sensing Receptor Is Involved in Follicle-Stimulating Hormone-Induced Cumulus Expansion in in vitro Cultured Porcine Cumulus-Oocyte Complexes

Frontiers in Cell and Developmental Biology, 2021
The Calcium-Sensing Receptor (CASR) is a G protein-coupled receptor of the C family that reportedly promotes maturation of porcine oocytes. However, its role in cumulus expansion of cumulus-oocyte complexes (COCs) is not well known.
Huage Liu, Huage Liu, Dan Zhou, Cong Liu, Qingrui Zhuan, Yan Luo, Xianhong Mo, Xiangwei Fu, Yunpeng Hou   +8 more
doaj   +1 more source

The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination. [PDF]

J Biol Chem, 2010
Hyaluronan is a component of the extracellular matrix, which affects tissue homeostasis. In this study, we investigated the regulatory mechanisms of one of the hyaluronan-synthesizing enzymes, HAS2. Ectopic expression of Flag- and 6myc-HAS2 in COS-1 cells followed by immunoprecipitation and immunoblotting revealed homodimers; after co-transfection with
Karousou E, Kamiryo M, Skandalis SS, Ruusala A, Asteriou T, Passi A, Yamashita H, Hellman U, Heldin CH, Heldin P.   +9 more
europepmc   +5 more sources

Osteopontin Induction of Hyaluronan Synthase 2 Expression Promotes Breast Cancer Malignancy [PDF]

Journal of Biological Chemistry, 2006
Osteopontin (OPN) is a tumor-associated, secreted phosphoprotein that has been implicated in breast cancer progression and metastasis. Research concerning how OPN functions in tumor progression has led to the identification of a limited number of genes that contribute functionally to OPN-induced cellular behaviors. Recent microarray analysis, comparing
Amy C, Cook, Ann F, Chambers, Eva A, Turley, Alan B, Tuck   +3 more
openaire   +2 more sources

Immunohistochemical Analysis of IL-1 Receptor 1 In the Discs of Patients with Temporomandibular Joint Dysfunction [PDF]

, 2018
Objective Temporomandibular joint dysfunction (TMD) may affect a patient’s quality of life, and one of the etiologies can be anterior disc displacement with reduction (ADDwR) and anterior disc displacement without reduction (ADDWoR).
Almeida, Luis Eduardo, Bosio, Jose A, Butcher, Seth, Doetzer, Andrea, Hresko, Kyle, Leonardi, Rosalia, Lorento, Carla, Sorenson, Adam, Tayebi, Lobat   +8 more
core   +2 more sources

Fibroblast and keratinocyte gene expression following exposure to the extracts of holy basil plant (Ocimum tenuiflorum), malabar nut plant (Justicia adhatoda), and emblic myrobalan plant (Phyllanthus emblica)

Data in Brief, 2018
This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of holy basil plant (Ocimum tenuiflorum), sri lankan local name “maduruthala”, 0.1% and 0.01 ...
Takao Someya, Katsura Sano, Kotaro Hara, Yoshimasa Sagane, Toshihiro Watanabe, R.G.S. Wijesekara   +5 more
doaj   +1 more source

Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma [PDF]

BMC Cancer, 2010
Abstract Background Hyaluronan accumulation correlates with the degree of malignancy in many solid tumor types, including malignant endometrial carcinomas. To elucidate the mechanism of hyaluronan accumulation, we examined the expression levels of the hyaluronan synthases (HAS1, HAS2 and HAS3) and hyaluronidases ...
Kosma Veli-Matti, Hämäläinen Kirsi, Sironen Reijo, Tammi Raija H, Rilla Kirsi, Tammi Markku I, Nykopp Timo K, Heinonen Seppo, Anttila Maarit   +8 more
openaire   +3 more sources

Biological responses of three-dimensional cultured fibroblasts by sustained compressive loading include apoptosis and survival activity. [PDF]

PLoS ONE, 2014
Pressure ulcers are characterized by chronicity, which results in delayed wound healing due to pressure. Early intervention for preventing delayed healing due to pressure requires a prediction method.
Toshiki Kanazawa, Gojiro Nakagami, Takeo Minematsu, Takumi Yamane, Lijuan Huang, Yuko Mugita, Hiroshi Noguchi, Taketoshi Mori, Hiromi Sanada   +8 more
doaj   +1 more source

One-electron oxidation and reduction of glycosaminoglycan chloramides: a kinetic study. [PDF]

, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, these being significant components of the extracellular matrix (ECM).
A.W.J. Paterson, Akeel, Al-Assaf, Al-Assaf, B.J. Parsons, Balazs, C. Houee-Levin, Camenisch, Chawla, D.J. Heyes, Dogliotti, Eriksen, Hardingham, Hawkins, Hayon, Hayon, Heckel, Heinecke, Huie, Ivanov, J.-L. Marignier, Jiang, Johnson, Kennett, Kennett, Kettle, Laurent, Laurent, McElroy, McElroy, McGowan, Milner, Misra, Parsons, Parsons, Pattison, Pattison, Pattison, Pe Myint, Poskrebyshev, Redpath, Rees, Rees, Rees, Rees, Rees, Rees, S. Sibanda, Schwarz, Stern, Swallow, Tang, Thomas, Thomas, Thorne, Toole, Toole, Toole, Turley, van Golen, von Sonntag, Weeks, Weiss, Weiss, Wine, Wolfenden, Woods, Zao   +67 more
core   +1 more source