Results 31 to 40 of about 2,264,107 (292)

Workplaces of Today and Tomorrow to Attract and Retain Top Talent: Challenges and Opportunities with Remote / Hybrid Practices [PDF]

SocioEconomic Challenges
The face and nature of the workplace are changing; remote work technologies and the capabilities of artificial intelligence are having a transformative effect on traditional norms of work performance, to which both employees and managers must adapt.
Bahaudin G. Mujtaba, Eleanor T. Lawrence
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A Scoping Review of Research Exploring Working Life Practices of People with Disabilities During the COVID-19 Pandemic

Scandinavian Journal of Disability Research, 2023
There have been numerous research studies stating the fact that the pandemic affected people with disabilities’ working lives. Less research has been conducted on how people with disabilities coped with and learned from these challenges.
Magnus Eriksson, Elisabet M. Nilsson, Jörgen Lundälv   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Global trends in work location, before, during, and after COVID-19: office, home, hybrid, and nomad

Urban, Planning and Transport Research
The COVID-19 pandemic led to a sudden shift to digital remote work for most office workers worldwide. This article aims to survey and interpret global data on the shares of four workplace location options that have been adopted since the pandemic ...
Aharon Kellerman
doaj   +1 more source

Variations of work engagement and psychological distress based on three working modalities during the COVID-19 pandemic

Frontiers in Public Health, 2023
With the onset of the COVID-19 pandemic, the rapid spread of the SARS-CoV-2 virus became a global health threat affecting people’s mental and physical health, as well as working conditions and modalities.
Alejandro Unda-López, Clara Paz, Paula Hidalgo-Andrade, Paula Hidalgo-Andrade, Carlos Hermosa-Bosano   +4 more
doaj   +1 more source

Hybridization of a Mobile Work Machine [PDF]

World Electric Vehicle Journal, 2009
Interest to hybridize mobile work machines has increased substantially during ongoing decade. Reasons for increasing interest are mainly tightening emission regulations and trend of rising fuel prices. To get better understanding for the benefits of hybridization, Helsinki University of Technology (TKK) has started 5 years project to research different
Lehmuspelto, Teemu, Heiska, Matti, Leivo, Antti, Hentunen, Ari   +3 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source