Results 41 to 50 of about 2,258,629 (292)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Hybrid work – a reconceptualisation and research agenda

i-com
We begin this conceptual paper, by outlining three recent developments in the context of the changing the nature of work: (1) the increasing proportion of remote work, (2) the quickly expanding use of (generative) AI applications, and (3) the growing ...
Richter Alexander, Richter Shahper
doaj   +1 more source

Virtual leadership adaptation in times of crisis: a process framework from a South African higher education institution

Frontiers in Education
IntroductionThe COVID-19 crisis served as a disruptive catalyst for reimagining leadership in higher education institutions (HEIs), particularly within resource-constrained and traditionally contact-based environments.
Abdulbaqi Badru, Cecile Gerwel Proches, Christinah Mulaudzi   +2 more
doaj   +1 more source

The challenges of hybrid work: an architectural sociology perspective

Buildings & Cities, 2023
An unwanted experiment of prolonged periods of working away from the office was forced on many societies by the COVID-19 pandemic. In the three years since the COVID outbreak, many organisations have shifted to hybrid work practices by mixing working ...
Kerstin Sailer, Matt Thomas, Rosica Pachilova   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Working from Home: Increased Productivity or a Gateway to Counterproductivity? The Role of Personality Traits

Journal of Work and Organizational Psychology
As flexible work arrangements gain popularity, the effects of working from home (WFH) on employee behavior have become increasingly relevant. This study investigates how Big Five personality traits influence remote work productivity, cyberslacking, and ...
Sabrina Heyen, Christian Spoden
doaj   +1 more source

A General Spatio-Temporal Clustering-Based Non-local Formulation for Multiscale Modeling of Compartmentalized Reservoirs

, 2019
Representing the reservoir as a network of discrete compartments with neighbor and non-neighbor connections is a fast, yet accurate method for analyzing oil and gas reservoirs.
Castineira, David, Darabi, Hamed, Esmaeilzadeh, Soheil, Hetz, Gill, Olalotiti-lawal, Feyisayo, Salehi, Amir   +5 more
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source