Results 31 to 40 of about 569,346 (259)
Crafting From Home: A Qualitative Analysis of Job Characteristics and Job Crafting in Hybrid Work
Scandinavian Journal of Work and Organizational PsychologyWith the transition to hybrid work arrangements, employees experience altered job characteristics that increase the relevance of proactively shaping their work environment.
Katharina Sophie Apenbrink, Stefan Süß
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Remote work – the new normal needs more research
Scandinavian Journal of Work, Environment & HealthOne of the recent global crises has been the COVID-19 pandemic, drastically changing how we work in expert positions or otherwise do work that can be performed using mobile devices.
Annina Ropponen
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Administrative SciencesIn this study, we adopt the lens of routines, a core construct in the theory of organizations through which to view how enterprises respond to societal disruptions.
Turanay Caner, Ravi Madhavan
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Remote work and hybrid work organizations
, 2022 Remote work, especially working from home, has become the most common form of work in the third decade of the 21st century. What started at the beginning of the millennium as an experimental practice in some companies (mainly in the IT industry) has become widespread and unintentional in 2020 and 2021, due to Covid 19 pandemic.
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
The Consequences of Remote Work – a Comparison of Four Central European Countries
Comparative Economic ResearchThe article examines the similarities and differences in how employees across four Central European countries evaluate the consequences of remote work.
Małgorzata Król, Joanna Trzęsiok
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Competencies for leadership development in hybrid work environments
SA Journal of Human Resource ManagementOrientation: The exponential change experienced by organisations, driven by the Fourth Industrial Revolution (4IR) and accelerated by the coronavirus disease 2019 (COVID-19) pandemic, has transformed work arrangements and placed new demands on ...
Mmathema A.C. Matle, Karel Stanz
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source