Results 61 to 70 of about 14,665,680 (294)
Software Companies' Responses to Hybrid Working
2024 50th Euromicro Conference on Software Engineering and Advanced Applications (SEAA)COVID 19 pandemic has disrupted the global market and workplace landscape. As a response, hybrid work situations have become popular in the software business sector. This way of working has an impact on software companies. This study investigates software companies responses to hybrid working. We conducted a large scale survey to achieve our objective.
Dron Khanna +3 more
openaire +4 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Healthy Work Environment Ecosystems for Teleworking and Hybrid Working
Procedia Computer ScienceThe COVID-19 pandemic has brought global physical, psychological, social and occupational health challenges. Telework and hybrid work have been a necessary response that has sustained and transformed companies and work at a global level. The main objective of this paper is to understand and characterize how ecosystems of healthy work environments in ...
Tânia Gaspar +3 more
openaire +4 more sources
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
, 2022 The advancing digitalization and Covid-19 as one of the acceleration factors concerning digital transformation processes have strongly determined the pace of adaptability of work structures in the recent past. Companies no longer have the choice to adapt at their discretion concerning digital progress.
openaire +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
REINVENTING TIME AND SPACE IN THE HYBRID WORK AGE [PDF]
openIn a post-pandemic context, hybrid work is emerging as one of the most relevant solutions for rethinking work organization. This thesis explores the concept of hybrid work, analysing the implications for companies and employees in terms of space ...
BELLESSO, ALESSIA
core
Work and non-work boundary management including remote and hybrid working
The COVID-19 pandemic and the shift to remote and hybrid work arrangements have highlighted the importance of managing boundaries between work and non-work.
Chan, Xi Wen Carys, Kinman, Gail
core +1 more source
Harmony in hues: navigating work-life balance for creative parents in the UK’s hybrid landscape [PDF]
In the intricate dance of contemporary life, creative parents in the UK find themselves at a crossroads as the hybrid work landscape unfolds. This presentation delves into the nuanced challenges and opportunities faced by artistic minds, exploring the ...
Marshall, A.
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source