Results 81 to 90 of about 14,665,680 (294)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A low cost air hybrid concept [PDF]

, 2010
This article is a pre-print version of the full and final article which is available at the link below.Copyright © 2010 Institut français du pétrole Permission to make digital or hard copies of part or all of this work for personal or classroom use is ...
Lee, CY, Ma, T, Zhao H., Zhao, H, Lee C. Y., C. Y. Lee, H. Zhao, Ma T., T. Ma, Ma, T., Lee, C. Y., Zhao, H.   +11 more
core   +1 more source

Work models as an element of the employer brand in the Polish labour market

Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
The development of digital technologies and the experience of pandemics have transformed traditional work models. For some employees, the ability to work from outside the organization's headquarters has become a condition for employment.
Arkadiusz Gryko
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A Hybrid Investigative Ecology [PDF]

, 2023
In Part 2, we have looked at what we called ‘hybrid elements’ in emerging organisations focused on investigative journalism and holding power to account.
Konow Lund, Maria, Park, Michelle
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Curating salutogenic spaces in post-pandemic hybrid work environments: A photo-elicitation qualitative study [PDF]

This article investigates the lived experience of hybrid working and the impact this has on knowledge workers’ psychosocial health and wellbeing. Specifically, we focus on how the workplace can promote or hinder wellbeing and how hybrid working is ...
Charlotte von Bülow, Pike, Gemma, Harriet Shortt, von Bulow, Charlotte, Gemma Pike, McClean, Stuart, Stuart McClean, Shortt, Harriet   +7 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Practice and prospects of remote and hybrid work models in modern companies

Ученые записки Российской академии предпринимательства
The research of remote and hybrid formats of employees’ work in modern companies is carried out, advantages and disadvantages are revealed. The influence of different work formats on personnel involvement is considered.
Ya. A. Nikolski
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source