Results 51 to 60 of about 2,264,107 (292)

Critical Success Factors of Agile Software Development Projects in Hybrid Settings: A Mixed-Method Approach

open access: yesIEEE Access
The rapid shift to hybrid work challenges Agile software development teams, because agile methodologies were originally designed for co-located environments.
Saagarika Gosu   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Making hybrid work work

open access: yes, 2022
Während das Management virtueller- und klassischer Face-to-Face-Teams stark erforscht ist, gibt es nur wenig Literatur über hybride Teams. Da das Phänomen der hybriden Arbeit erst seit kurzem bekannt ist, werden in dieser Masterarbeit die häufigsten Probleme der hybriden Teamarbeit, die sich aus der massiven Verlagerung hin zu mehr Virtualität in Teams
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Advancing virtual and hybrid team well-being through a job demand-resources lens

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being
As the modern workplace evolves, the shift to virtual and hybrid team working necessitates a re-evaluation of well-being. While workplace well-being research has predominantly focused on the individual level, understanding team-level well-being is ...
Cass Coulston   +3 more
doaj   +1 more source

Experimental study and numerical modelling of woven fabric kenaf fiber composites hybrid adhesively bonded-bolted joints [PDF]

open access: yes, 2018
Couple with natural fiber composite parts, hybrid joints provide better joint strength than using separate joints. There are limited studies on structures response and strength prediction work on hybrid joints that limits its applicability.
Lee, Sim Yee
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A Hybrid High-Order method for Leray-Lions elliptic equations on general meshes

open access: yes, 2016
In this work, we develop and analyze a Hybrid High-Order (HHO) method for steady non-linear Leray-Lions problems. The proposed method has several assets, including the support for arbitrary approximation orders and general polytopal meshes.
Di Pietro, Daniele A., Droniou, Jérôme
core   +4 more sources

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